Concepedia

Type I Interferon Induction

Type I Interferon Induction is a molecular signaling event within the innate immune response that is specifically initiated by RIG-I-like receptors upon detection of viral RNA, leading to the activation of transcription factors responsible for the production of type I interferons.

2K

Publications

178.8K

Citations

10K

Authors

1.9K

Institutions

Publications per year

2017–2026

412

Parents

Publications

2K

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

Lijun Sun, Jiaxi Wu, Fenghe Du et al. · Science · 2012 · 4.8K citations

, , +16

Virus interference. I. The interferon

Alick Isaacs, J. Lindenmann · Proceedings of the Royal Society of London. Series B, Biological sciences · 1957 · 3.4K citations

, , +17

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

Hiroki Ishikawa, Zhe Ma, Glen N. Barber · Nature · 2009 · 2.7K citations · Full text

, , +14

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

Taro Kawai, Ken Takahashi, Shintaro Sato et al. · Nature Immunology · 2005 · 2.5K citations

, , +12

IRF-7 is the master regulator of type-I interferon-dependent immune responses

Kenya Honda, Hideyuki Yanai, Hideo Negishi et al. · Nature · 2005 · 2.2K citations

, , +13

1–5 of 2K

Authors

10K

  1. SA
    Shizuo Akira

    The University of Osaka, Japan

    23 publications · 8.1K citations

    22

    h-index

  2. AG
    Adolfo García‐Sastre

    Icahn School of Medicine at Mount Sinai, United States

    25 publications · 2.5K citations

    21

    h-index

  3. PM
    Paula M. Pitha

    Johns Hopkins University, United States

    29 publications · 2.2K citations

    21

    h-index

  4. UK
    Ulrich Kalinke

    Center for Experimental and Clinical Infection Research, Germany

    23 publications · 2.8K citations

    20

    h-index

  5. GC
    Ganes C. Sen

    Cleveland Clinic, United States

    21 publications · 1.6K citations

    20

    h-index

1–5 of 10K

Institutions

1.9K

  1. Icahn School of Medicine at Mount Sinai

    New York, United States

    35 h-index

    169 publications

    15.4K citations

  2. National Institutes of Health

    Bethesda, United States

    35 h-index

    216 publications

    20K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    33 h-index

    214 publications

    23.1K citations

  4. The University of Osaka

    Osaka, Japan

    32 h-index

    143 publications

    52.5K citations

  5. Inserm

    Paris, France

    32 h-index

    178 publications

    16.6K citations

  6. Washington University in St. Louis

    St Louis, United States

    31 h-index

    123 publications

    30.9K citations

  7. Howard Hughes Medical Institute

    Chevy Chase, United States

    30 h-index

    69 publications

    41.2K citations

  8. Institut Pasteur

    Paris, France

    30 h-index

    112 publications

    12.7K citations

1–8 of 1.9K

Venues

  1. Journal of Virology

    JVI · 220 publications · 17.8K citations

    81

    h-index

  2. Journal of Biological Chemistry

    JBC · 88 publications · 9.7K citations

    57

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 64 publications · 8.4K citations

    51

    h-index

  4. Virology

    92 publications · 5.2K citations

    42

    h-index

  5. PLoS Pathogens

    49 publications · 4.8K citations

    37

    h-index

1–5