Paula M. Pitha

LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF

Katherine A. Fitzgerald, Daniel C. Rowe, Betsy Barnes et al. · The Journal of Experimental Medicine · 2003 · 1.2K citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Virus-Dependent Phosphorylation of the IRF-3 Transcription Factor Regulates Nuclear Translocation, Transactivation Potential, and Proteasome-Mediated Degradation

Rongtuan Lin, Christophe Heylbroeck, Paula M. Pitha et al. · Molecular and Cellular Biology · 1998 · 919 citations

Life Sciences, Cell Biology, Molecular Biology +16

E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas.

Jeremy R. Graff, James G. Herman, Rena G. Lapidus et al. · PubMed · 1995 · 801 citations

Life Sciences, Cancer Biology, Molecular Biology +14

Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus.

Andrew P. Lieberman, Paula M. Pitha, H. S. Shin et al. · Proceedings of the National Academy of Sciences · 1989 · 787 citations · Full text

Life Sciences, Immunology, Neuroscience +17

Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of Toll-like receptor 7

Jong‐Dae Lee, Tsung‐Hsien Chuang, Vanessa Redecke et al. · Proceedings of the National Academy of Sciences · 2003 · 586 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17