Rena G. Lapidus

Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers.

James G. Herman, Adrian Merlo, Li Mao et al. · PubMed · 1995 · 1.4K citations

Epigenetic Change, Dna Methylation, Aberrant Dna Methylation +17

E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas.

Jeremy R. Graff, James G. Herman, Rena G. Lapidus et al. · PubMed · 1995 · 801 citations

Breast Oncology, Pathology, E-cad Promoter Region +16

Demethylation of the estrogen receptor gene in estrogen receptor-negative breast cancer cells can reactivate estrogen receptor gene expression.

Anne Ferguson, Rena G. Lapidus, Stephen B. Baylin et al. · PubMed · 1995 · 302 citations

Er Gene Expression, Systems Biology, Estrogen Receptor Gene +14

Methylation of estrogen and progesterone receptor gene 5' CpG islands correlates with lack of estrogen and progesterone receptor gene expression in breast tumors.

Rena G. Lapidus, Anne Ferguson, Yvonne Ottaviano et al. · PubMed · 1996 · 254 citations

Breast Oncology, Epigenetic Change, Genetics +16

Mapping of ER gene CpG island methylation-specific polymerase chain reaction.

Rena G. Lapidus, Sharyl J. Nass, K A Butash et al. · PubMed · 1998 · 210 citations

Breast Oncology, Epigenetic Change, Genetics +19