Anne Ferguson

High frequency of hypermethylation at the 14-3-3 σ locus leads to gene silencing in breast cancer

Anne Ferguson, Ella Evron, Christopher B. Umbricht et al. · Proceedings of the National Academy of Sciences · 2000 · 442 citations

Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells.

Xiaowei Yang, Dawn L. Phillips, Anne Ferguson et al. · PubMed · 2001 · 425 citations

Functional Estrogen Receptor, Breast Oncology, Epigenetic Change +22

Demethylation of the estrogen receptor gene in estrogen receptor-negative breast cancer cells can reactivate estrogen receptor gene expression.

Anne Ferguson, Rena G. Lapidus, Stephen B. Baylin et al. · PubMed · 1995 · 302 citations

Er Gene Expression, Systems Biology, Estrogen Receptor Gene +14

Hypermethylation of 14-3-3 σ (stratifin) is an early event in breast cancer

Christopher B. Umbricht, Ella Evron, Edward Gabrielson et al. · Oncogene · 2001 · 288 citations

Tumor Biology, Breast Oncology, Medicine +9

Methylation of estrogen and progesterone receptor gene 5' CpG islands correlates with lack of estrogen and progesterone receptor gene expression in breast tumors.

Rena G. Lapidus, Anne Ferguson, Yvonne Ottaviano et al. · PubMed · 1996 · 254 citations

Breast Oncology, Epigenetic Change, Genetics +16