Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

Lena Alexopoulou, Agnieszka Czopik Holt, Ruslan Medzhitov, +1

Nature

InflammationToll-like ReceptorsMolecular ImmunologyCytokineAllergy +12

Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8

Florian Heil, Hiroaki Hemmi, Hubertus Hochrein, +6

Science

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

Mitsutoshi Yoneyama, Mika Kikuchi, Takashi Natsukawa, +6

Nature Immunology

Essential FunctionViral ReplicationMolecular VirologyNatural SciencesImmunology +8

Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA

Sandra S. Diebold, Tsuneyasu Kaisho, Hiroaki Hemmi, +2

Science

Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway

Masahiro Yamamoto, Shintaro Sato, Hiroaki Hemmi, +8

Science

IKKε and TBK1 are essential components of the IRF3 signaling pathway

Katherine A. Fitzgerald, Sarah M. McWhirter, L. Kerrie, +6

Nature Immunology

Signal TransductionSignaling PathwayCell RegulationMolecular RegulationGene Expression +7

Triggering the Interferon Antiviral Response Through an IKK-Related Pathway

Sonia Sharma, Benjamin R. tenOever, Nathalie Grandvaux, +3

Science

Ikappab KinaseSignal TransductionRapid InductionInterferon Antiviral ResponseReceptor Tyrosine Kinase +12

Cell Type-Specific Involvement of RIG-I in Antiviral Response

Hiroki Kato, Shintaro Sato, Mitsutoshi Yoneyama, +8

Immunity

Cell Type-specific InvolvementImmunologyAntiviral Drug DevelopmentAntiviral ResponseVirology +4

Cutting Edge: A Novel Toll/IL-1 Receptor Domain-Containing Adapter That Preferentially Activates the IFN-β Promoter in the Toll-Like Receptor Signaling

Masahiro Yamamoto, Shintaro Sato, Kiyotoshi Mori, +4

The Journal of Immunology

Innate Immune SystemImmunologyToll-like ReceptorImmunologic MechanismInnate Immunity +17

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3–mediated interferon-β induction

Hiroyuki Oshiumi, Misako Matsumoto, Kenji Funami, +2

Nature Immunology

InflammationToll-like ReceptorsMolecular ImmunologyCytokineSignal Transduction +12