Ken J. Ishii

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

Hiroki Kato, Osamu Takeuchi, Shintaro Sato et al. · Nature · 2006 · 3.8K citations

Rig-i Helicases, Virus Structure, Viral Replication +11

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

Taro Kawai, Ken Takahashi, Shintaro Sato et al. · Nature Immunology · 2005 · 2.5K citations

Mda5-mediated Type, Signal Transduction, Natural Sciences +6

Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

Taro Kawai, Shintaro Sato, Ken J. Ishii et al. · Nature Immunology · 2004 · 1K citations

Inflammation, Toll-like Receptors, Molecular Immunology +14

Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response

Tatsuya Saitoh, Naonobu Fujita, Takuya Hayashi et al. · Proceedings of the National Academy of Sciences · 2009 · 821 citations · Full text

Microbial Nucleic Acids, Molecular Regulation, Genetics +20

A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNA

Ken J. Ishii, Cevayir Coban, Hiroki Kato et al. · Nature Immunology · 2005 · 757 citations

Toll-like Receptors, Molecular Virology, Immunology +9