Florian Heil

Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8

Florian Heil, Hiroaki Hemmi, Hubertus Hochrein et al. · Science · 2004 · 3.9K citations

Life Sciences, Immunology, Molecular Biology +17

Effect of the MDM2 antagonist RG7112 on the P53 pathway in patients with MDM2-amplified, well-differentiated or dedifferentiated liposarcoma: an exploratory proof-of-mechanism study

Isabelle Ray‐Coquard, Jean‐Yves Blay, Antoîne Italiano et al. · The Lancet Oncology · 2012 · 563 citations

Medicine, Cancer Biology, Oncology +16

The Toll‐like receptor 7 (TLR7)‐specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily

Florian Heil, Parviz Ahmad‐Nejad, Hiroaki Hemmi et al. · European Journal of Immunology · 2003 · 515 citations · Full text

Life Sciences, Immunology, Pharmacology +17

First-in-human phase I clinical trial of RG7356, an anti-CD44 humanized antibody, in patients with advanced, CD44-expressing solid tumors

C. Willemien Menke‐van der Houven van Oordt, Carlos Gomez-Roca, Carla van Herpen et al. · Oncotarget · 2016 · 156 citations · Full text

Medicine, Cancer Biology, Oncology +14

First-in-Human Phase I Study of Single-agent Vanucizumab, A First-in-Class Bispecific Anti-Angiopoietin-2/Anti-VEGF-A Antibody, in Adult Patients with Advanced Solid Tumors

Manuel Hidalgo, Maria Martinez‐García, Christophe Le Tourneau et al. · Clinical Cancer Research · 2017 · 102 citations

Medicine, Oncology, Pharmacology +17