2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members

Stéphane Daffis, Kristy J. Szretter, Jill Schriewer, +16

Nature

Viral ReplicationMolecular VirologyIfit Family MembersMedicineGenetics +9

The interferon system. A bird's eye view of its biochemistry.

Ganes C. Sen, Péter Lengyel

Journal of Biological Chemistry

BiologyNatural SciencesBioanalysisMolecular BiologyBiochemical Interaction +3

Transcriptional Profiling of Interferon Regulatory Factor 3 Target Genes: Direct Involvement in the Regulation of Interferon-Stimulated Genes

Nathalie Grandvaux, Marc J. Servant, Benjamin R. tenOever, +5

Journal of Virology

Attenuation of c <scp>GAS</scp> ‐ <scp>STING</scp> signaling is mediated by a p62/ <scp>SQSTM</scp> 1‐dependent autophagy pathway activated by TBK1

Thaneas Prabakaran, Chiranjeevi Bodda, Christian Krapp, +18

The EMBO Journal

Cell AutophagyTranscriptional RegulationMitophagySignal TransductionSystems Biology +11

Toll-like receptor 3-mediated activation of NF-κB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-β

Zhengfan Jiang, Tak W. Mak, Ganes C. Sen, +1

Proceedings of the National Academy of Sciences

Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling

Saumendra N. Sarkar, Kristi L. Peters, Christopher P. Elco, +3

Nature Structural & Molecular Biology

Pi3 KinaseSignal TransductionSignaling PathwayDouble-stranded Rna SignalingNatural Sciences +10

Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA

Shoudong Li, Ji-Young Min, Robert M. Krug, +1

Virology

Viral ReplicationMolecular BiologyVirologyDouble-stranded RnaSystems Biology +3

Interferon, double-stranded RNA, and protein phosphorylation.

Bernard Lebleu, Ganes C. Sen, S Shaila, +2

Proceedings of the National Academy of Sciences

Transcriptional RegulationSystems BiologyEngineeringMedicineRna Binding Proteins +10

A site on the influenza A virus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis

Ji-Young Min, Shoudong Li, Ganes C. Sen, +1

Virology

Viral ReplicationNatural SciencesMolecular BiologyVirologyViral Rna Synthesis +7

Viral apoptosis is induced by IRF‐3‐mediated activation of Bax

Saurabh Chattopadhyay, João T. Marques, M Yamashita, +5

The EMBO Journal