Zhengfan Jiang

Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy

Mengze Lv, Meixia Chen, Rui Zhang et al. · Cell Research · 2020 · 927 citations · Full text

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

Wenxiang Sun, Yang Li, Lu Chen et al. · Proceedings of the National Academy of Sciences · 2009 · 834 citations · Full text

Innate Immune System, Immunology, Molecular Biology +17

Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses

Chenguang Wang, Yukun Guan, Mengze Lv et al. · Immunity · 2018 · 739 citations · Full text

Chromatin, Double-stranded Dna, Nucleic Acid Chemistry +13

CD14 is required for MyD88-independent LPS signaling

Zhengfan Jiang, Philippe Georgel, Xin Du et al. · Nature Immunology · 2005 · 666 citations

Myd88-independent Lps, Signal Transduction, Signaling Pathway +6

STING directly activates autophagy to tune the innate immune response

Dong Liu, Hao Wu, Chenguang Wang et al. · Cell Death and Differentiation · 2018 · 387 citations · Full text

Inflammation, Cell Autophagy, Host Response +12