Tak W. Mak

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

Young‐Yun Kong, Hiroki Yoshida, Ildiko Sarosi et al. · Nature · 1999 · 3.4K citations

Medicine, Cell Biology, Immunology +14

Induction and Activation of the Transcription Factor NFATc1 (NFAT2) Integrate RANKL Signaling in Terminal Differentiation of Osteoclasts

Hiroshi Takayanagi, Sunhwa Kim, Takako Koga et al. · Developmental Cell · 2002 · 2.7K citations · Full text

Medicine, Cell Biology, Molecular Biology +16

Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN

Vuk Stambolic, Akira Suzuki, José Luís de la Pompa et al. · Cell · 1998 · 2.6K citations · Full text

Life Sciences, Cell Biology, Oncology +16

Immunologic Self-Tolerance Maintained by Cd25+Cd4+Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4

Takeshi Takahashi, Tomoyuki Tagami, Sayuri Yamazaki et al. · The Journal of Experimental Medicine · 2000 · 2.2K citations · Full text

Life Sciences, Immunology, Pathology +17

Acetylcholine-Synthesizing T Cells Relay Neural Signals in a Vagus Nerve Circuit

Mauricio Rosas‐Ballina, Peder S. Olofsson, Mahendar Ochani et al. · Science · 2011 · 1.5K citations · Full text

Life Sciences, Immunology, Neuroscience +17