Concepedia

Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN

Vuk Stambolic, Akira Suzuki, José Luís de la Pompa, Greg M. Brothers, Christine Mirtsos, Takehiko Sasaki, Jürgen Ruland, Josef Penninger, David P. Siderovski, Tak W. Mak

Cell · 1998 · 2.6K citations · 51 references

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51

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

Yael Gavrieli, Yoav Sherman, Shmuel A. Ben‐Sasson · The Journal of Cell Biology · 1992 · 9.5K citations · Full text

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Darren A.E. Cross, Dario R. Alessi, Philip Cohen et al. · Nature · 1995 · 5.2K citations

, , +12

<i>PTEN</i> , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

Jing Li, Clifford Yen, Danny Liaw et al. · Science · 1997 · 4.8K citations

, , +16

The Tumor Suppressor, PTEN/MMAC1, Dephosphorylates the Lipid Second Messenger, Phosphatidylinositol 3,4,5-Trisphosphate

Tomohiko Maehama, Jack E. Dixon · Journal of Biological Chemistry · 1998 · 3.1K citations · Full text

, , +17

Mechanism of activation of protein kinase B by insulin and IGF‐1.

Dario R. Alessi, Mirjana Andjelković, B. Caudwell et al. · The EMBO Journal · 1996 · 3K citations · Full text

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