Concepedia

Primary Drying Endpoint Detection

Primary Drying Endpoint Detection is a methodological construct in freeze-drying research that identifies the precise moment when the sublimation phase of ice concludes, distinguishing itself from other drying monitoring techniques by its specificity to the completion of primary drying in lyophilization processes.

17

Publications

785

Citations

52

Authors

17

Institutions

Publications per year

2017–2026

8

Parents

Publications

17

Determination of End Point of Primary Drying in Freeze-Drying Process Control

Sajal M. Patel, Takayuki Doen, Michael J. Pikal · AAPS PharmSciTech · 2010 · 269 citations · Full text

, , +15

Monitoring of the primary drying of a lyophilization process in vials

Antonello Barresi, Roberto Pisano, Davide Fissore et al. · Chemical Engineering and Processing - Process Intensification · 2008 · 110 citations · Full text

, , +11

Process control in freeze drying: determination of the end point of sublimation drying by an electronic moisture sensor.

Michael L. Roy, Michael J. Pikal · PubMed · 1989 · 99 citations

, , +16

In-line monitoring of the primary drying phase of the freeze-drying process in vial by means of a Kalman filter based observer

Salvatore Velardi, H. Hammouri, Antonello Barresi · Process Safety and Environmental Protection · 2009 · 52 citations · Full text

, , +17

A primary drying model-based comparison of conventional batch freeze-drying to continuous spin-freeze-drying for unit doses

Laurens Leys, Brecht Vanbillemont, Pieter-Jan Van Bockstal et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2020 · 42 citations

, , +14

1–5 of 17

Authors

52

  1. MJ
    Michael J. Pikal

    University of Connecticut, United States

    3 publications · 387 citations

    3

    h-index

  2. RP
    Roberto Pisano

    Politecnico di Torino, Italy

    2 publications · 145 citations

    2

    h-index

  3. SV
    Salvatore Velardi

    Politecnico di Torino, Italy

    2 publications · 162 citations

    2

    h-index

  4. AJ
    Alex Juckers

    Clausthal University of Technology, Germany

    2 publications · 35 citations

    2

    h-index

  5. AR
    A. Ryniecki

    University of Life Sciences in Poznań, Poland

    1 publications · 15 citations

    2

    h-index

1–5 of 52

Institutions

17

  1. Politecnico di Torino

    Turin, Italy

    3 h-index

    10 publications

    909 citations

  2. University of Connecticut

    Storrs, United States

    2 h-index

    7 publications

    883 citations

  3. Clausthal University of Technology

    Clausthal-Zellerfeld, Germany

    2 h-index

    4 publications

    70 citations

  4. Physical Sciences (United States)

    Andover, United States

    1 h-index

    1 publications

    19 citations

  5. Laboratoire d'Automatique, de Génie des Procédés et de Génie Pharmaceutique

    Villeurbanne, France

    1 h-index

    1 publications

    52 citations

  6. Université Claude Bernard Lyon 1

    Villeurbanne, France

    1 h-index

    1 publications

    52 citations

  7. Pfizer (United States)

    New York, United States

    1 h-index

    2 publications

    26 citations

  8. Kookmin University

    Seoul, South Korea

    1 h-index

    3 publications

    39 citations

1–8 of 17

Venues

  1. European Journal of Pharmaceutics and Biopharmaceutics

    EJPB · 2 publications · 53 citations

    2

    h-index

  2. Journal of Pharmaceutical Sciences

    2 publications · 32 citations

    2

    h-index

  3. Powder Technology

    1 publications · 13 citations

    1

    h-index

  4. Process Safety and Environmental Protection

    1 publications · 52 citations

    1

    h-index

  5. Drying Technology

    1 publications · 35 citations

    1

    h-index

1–5