Michael L. Roy

Mass and Heat Transfer in Vial Freeze-Drying of Pharmaceuticals: Role of the Vial

Michael J. Pikal, Michael L. Roy, Saroj Shah · Journal of Pharmaceutical Sciences · 1984 · 335 citations

Engineering, Desiccation, Pharmaceutical Technology +7

Evaluation of manometric temperature measurement as a method of monitoring product temperature during lyophilization.

Nathaniel Milton, Michael J. Pikal, Michael L. Roy et al. · PubMed · 1997 · 155 citations

Primary Drying, Engineering, Measurement +17

Solid state chemistry of proteins: II. The correlation of storage stability of freeze‐dried human growth hormone (hGH) with structure and dynamics in the glassy solid

Michael J. Pikal, Daniel R. Rigsbee, Michael L. Roy et al. · Journal of Pharmaceutical Sciences · 2008 · 106 citations

Protein Chemistry, Storage Stability, Biochemistry +3

Formulation and stability of freeze-dried proteins: effects of moisture and oxygen on the stability of freeze-dried formulations of human growth hormone.

Michael J. Pikal, Karen M. Dellerman, Michael L. Roy · PubMed · 1992 · 102 citations

Human Growth, Food Analysis, Methionine Oxidation +20

Process control in freeze drying: determination of the end point of sublimation drying by an electronic moisture sensor.

Michael L. Roy, Michael J. Pikal · PubMed · 1989 · 99 citations

Primary Drying, Engineering, Measurement +19