Concepedia

Primary Drying End Point

Primary Drying End Point is a process-determination construct in lyophilization that denotes the termination point of the primary drying phase, identified by the cessation of sublimation when the majority of frozen solvent has been removed from the product under controlled vacuum and temperature conditions.

34

Publications

2.1K

Citations

137

Authors

44

Institutions

Publications per year

2017–2026

16

Variants

Primary Drying Endpoint

Parents

Publications

34

The ice nucleation temperature determines the primary drying rate of lyophilization for samples frozen on a temperature‐controlled shelf

James A. Searles, John F. Carpenter, Theodore W. Randolph · Journal of Pharmaceutical Sciences · 2001 · 392 citations

, , +14

Determination of End Point of Primary Drying in Freeze-Drying Process Control

Sajal M. Patel, Takayuki Doen, Michael J. Pikal · AAPS PharmSciTech · 2010 · 269 citations · Full text

, , +15

Controlled nucleation in freeze‐drying: Effects on pore size in the dried product layer, mass transfer resistance, and primary drying rate

Alex K. Konstantinidis, Wei Y. Kuu, Lori Otten et al. · Journal of Pharmaceutical Sciences · 2011 · 142 citations

, , +17

Lyophilization of protein formulations in vials: Investigation of the relationship between resistance to vapor flow during primary drying and small‐scale product collapse

David E. Overcashier, Thomas W. Patapoff, Chung C. Hsu · Journal of Pharmaceutical Sciences · 1999 · 112 citations

, , +16

Advanced approach to build the design space for the primary drying of a pharmaceutical freeze‐drying process

Davide Fissore, Roberto Pisano, Antonello Barresi · Journal of Pharmaceutical Sciences · 2011 · 111 citations

, , +15

1–5 of 34

Authors

137

  1. RP
    Roberto Pisano

    Politecnico di Torino, Italy

    4 publications · 341 citations

    4

    h-index

  2. JC
    Jos Corver

    Ghent University, Belgium

    4 publications · 72 citations

    4

    h-index

  3. TD
    Thomas De Beer

    Ghent University, Belgium

    4 publications · 72 citations

    4

    h-index

  4. DF
    Davide Fissore

    Politecnico di Torino, Italy

    3 publications · 306 citations

    3

    h-index

  5. IN
    Ingmar Nopens

    Ghent University, Belgium

    3 publications · 58 citations

    3

    h-index

1–5 of 137

Institutions

44

  1. Ghent University

    Ghent, Belgium

    4 h-index

    26 publications

    452 citations

  2. Politecnico di Torino

    Turin, Italy

    4 h-index

    14 publications

    1.4K citations

  3. Pfizer (United States)

    New York, United States

    3 h-index

    12 publications

    857 citations

  4. Clausthal University of Technology

    Clausthal-Zellerfeld, Germany

    2 h-index

    4 publications

    70 citations

  5. Technical University of Denmark

    Kongens Lyngby, Denmark

    2 h-index

    2 publications

    42 citations

  6. Bristol-Myers Squibb (United States)

    New York, United States

    2 h-index

    8 publications

    248 citations

  7. University of Connecticut

    Storrs, United States

    2 h-index

    4 publications

    864 citations

  8. University of Ljubljana

    Ljubljana, Slovenia

    2 h-index

    8 publications

    224 citations

1–8 of 44

Venues

  1. Journal of Pharmaceutical Sciences

    8 publications · 915 citations

    8

    h-index

  2. International Journal of Pharmaceutics

    3 publications · 48 citations

    3

    h-index

  3. Drying Technology

    3 publications · 133 citations

    3

    h-index

  4. Pharmaceutical Research

    3 publications · 136 citations

    3

    h-index

  5. PubMed

    Repository · 2 publications · 149 citations

    2

    h-index

1–5