Concepedia

Phenotypic Screening

Phenotypic Screening is an experimental strategy in chemical genetics, chemical genomics, and drug discovery that identifies bioactive small molecules by systematically assaying their effects on observable cellular or organismal phenotypes, typically without requiring prior knowledge of specific molecular targets or mechanisms of action.

262

Publications

16.3K

Citations

1.8K

Authors

644

Institutions

Publications per year

2017–2026

64

Parents

Children

Publications

262

The Chemical Genomic Portrait of Yeast: Uncovering a Phenotype for All Genes

Maureen E. Hillenmeyer, Eula Fung, Jan Wildenhain et al. · Science · 2008 · 1K citations · Full text

, , +17

Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment

Derek C. Rogers, Elizabeth Fisher, Steve D. M. Brown et al. · Mammalian Genome · 1997 · 803 citations

, , +11

Phenotype MicroArrays for High-Throughput Phenotypic Testing and Assay of Gene Function

Barry R. Bochner, Peter Gadzinski, Eugenia Panomitros · Genome Research · 2001 · 708 citations · Full text

, , +17

Genome-wide Generation and Systematic Phenotyping of Knockout Mice Reveals New Roles for Many Genes

Jacqueline K. White, Anna-Karin Gerdin, Natasha A. Karp et al. · Cell · 2013 · 542 citations · Full text

, , +17

Laboratory standards and guidelines for population-based cystic fibrosis carrier screening

Wayne W. Grody, Garry R. Cutting, K. Klinger et al. · Genetics in Medicine · 2001 · 460 citations

, , +13

1–5 of 262

Authors

1.8K

  1. MH
    Martin Hrabě de Angelis

    Helmholtz Zentrum München, Germany

    3 publications · 150 citations

    3

    h-index

  2. BR
    Birgit Rathkolb

    Ludwig-Maximilians-Universität München, Germany

    3 publications · 150 citations

    3

    h-index

  3. RT
    Randall T. Peterson

    Harvard University, United States

    3 publications · 250 citations

    3

    h-index

  4. EW
    Eckhard Wolf

    Ludwig-Maximilians-Universität München, Germany

    3 publications · 150 citations

    3

    h-index

  5. RH
    Ruili Huang

    National Institutes of Health, United States

    3 publications · 130 citations

    3

    h-index

1–5 of 1.8K

Institutions

644

  1. Harvard University

    Cambridge, United States

    10 h-index

    23 publications

    2K citations

  2. Inserm

    Paris, France

    6 h-index

    25 publications

    1.5K citations

  3. Massachusetts General Hospital

    Boston, United States

    5 h-index

    22 publications

    3.1K citations

  4. Eli Lilly (United States)

    Indianapolis, United States

    5 h-index

    19 publications

    1K citations

  5. University of California, San Francisco

    San Francisco, United States

    5 h-index

    26 publications

    1.5K citations

  6. Broad Institute

    Cambridge, United States

    5 h-index

    33 publications

    3.6K citations

  7. University of Copenhagen

    Copenhagen, Denmark

    4 h-index

    10 publications

    224 citations

  8. Royal Children's Hospital

    Melbourne, Australia

    4 h-index

    17 publications

    925 citations

1–8 of 644

Venues

  1. SLAS DISCOVERY

    14 publications · 621 citations

    13

    h-index

  2. PubMed

    Repository · 10 publications · 396 citations

    10

    h-index

  3. PLoS ONE

    8 publications · 337 citations

    8

    h-index

  4. Scientific Reports

    6 publications · 246 citations

    6

    h-index

  5. Methods in molecular biology

    Book series · 6 publications · 159 citations

    5

    h-index

1–5