Concepedia

Disease Model Screening

Disease Model Screening is a phenotypic screening approach that employs biologically relevant models of human disease to identify compounds or genetic perturbations with therapeutic potential based on their ability to modify disease-associated phenotypes.

33

Publications

1.8K

Citations

252

Authors

104

Institutions

Publications per year

2017–2026

12

Parents

Publications

33

Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium

Terrence F. Meehan, Nathalie Conte, David B. West et al. · Nature Genetics · 2017 · 268 citations · Full text

, , +16

Zebrafish: from disease modeling to drug discovery.

Amy L. Rubinstein · PubMed · 2003 · 210 citations

, , +13

Biowire Model of Interstitial and Focal Cardiac Fibrosis

Erika Yan Wang, Naimeh Rafatian, Yimu Zhao et al. · ACS Central Science · 2019 · 131 citations · Full text

, , +16

Validation of corneally kindled mice: a sensitive screening model for partial epilepsy in man

Alain Matagne, Henrik Klitgaard · Epilepsy Research · 1998 · 127 citations

, , +8

Disease-specific induced pluripotent stem cells: a platform for human disease modeling and drug discovery

Jiho Jang, Jeong-Eun Yoo, Jeong‐Ah Lee et al. · Experimental & Molecular Medicine · 2012 · 104 citations · Full text

, , +15

1–5 of 33

Authors

252

  1. DK
    Dae‐Sung Kim

    Korea University, South Korea

    1 publications · 104 citations

    1

    h-index

  2. MJ
    Monica J. Justice

    Jackson Laboratory, United States

    1 publications · 268 citations

    1

    h-index

  3. JM
    Jackie Morizet

    Institut Gustave Roussy, France

    1 publications · 58 citations

    1

    h-index

  4. HC
    Haifeng Cheng

    Second Affiliated Hospital of Zhejiang University, China

    1 publications · 19 citations

    1

    h-index

  5. RN
    Ralf Nauen

    Bayer (Germany), Germany

    1 publications · 39 citations

    1

    h-index

1–5 of 252

Institutions

104

  1. Inserm

    Paris, France

    3 h-index

    5 publications

    898 citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    3 publications

    247 citations

  3. Broad Institute

    Cambridge, United States

    2 h-index

    16 publications

    1.1K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    4 publications

    862 citations

  5. University of California San Diego

    San Diego, United States

    2 h-index

    3 publications

    155 citations

  6. Baylor College of Medicine

    Houston, United States

    2 h-index

    8 publications

    1.6K citations

  7. Bayer (Germany)

    Leverkusen, Germany

    2 h-index

    12 publications

    360 citations

  8. Boston Children's Hospital

    Boston, United States

    2 h-index

    12 publications

    896 citations

1–8 of 104

Venues

  1. PubMed

    Repository · 3 publications · 278 citations

    3

    h-index

  2. Frontiers in Pharmacology

    2 publications · 67 citations

    2

    h-index

  3. Human Molecular Genetics

    2 publications · 179 citations

    2

    h-index

  4. Communications Biology

    1 publications · 38 citations

    1

    h-index

  5. Pesticide Biochemistry and Physiology

    PBP · 1 publications · 39 citations

    1

    h-index

1–5