Concepedia

Organoid Screening

Organoid Screening is a phenotypic screening method that utilizes three-dimensional, miniaturized, and self-organizing organ-like structures derived from stem or progenitor cells to model tissue-specific or disease-relevant phenotypes for drug discovery and functional analysis.

123

Publications

9.5K

Citations

1.2K

Authors

335

Institutions

Publications per year

2017–2026

120

Variants

Organoid-based Screening

Parents

Publications

123

A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology

Katrin P. Guillen, Maihi Fujita, Andrew Butterfield et al. · Nature Cancer · 2022 · 397 citations · Full text

, , +17

High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell–Derived Organoids

Tadahiro Shinozawa, Masaki Kimura, Yuqi Cai et al. · Gastroenterology · 2020 · 356 citations · Full text

, , +14

Patient derived organoids to model rare prostate cancer phenotypes

Loredana Puca, Rohan Bareja, Davide Prandi et al. · Nature Communications · 2018 · 356 citations · Full text

, , +17

Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway

Richard J. Mills, Benjamin L. Parker, Gregory A. Quaife-Ryan et al. · Cell stem cell · 2019 · 302 citations · Full text

, , +9

Mouse and human urothelial cancer organoids: A tool for bladder cancer research

Jasper Mullenders, Evelien de Jongh, Anneta Brousali et al. · Proceedings of the National Academy of Sciences · 2019 · 283 citations · Full text

, , +16

1–5 of 123

Authors

1.2K

  1. HC
    Hans Clevers

    Hubrecht Institute for Developmental Biology and Stem Cell Research, Netherlands

    10 publications · 1.2K citations

    10

    h-index

  2. AA
    Anthony Atala

    Wake Forest University, United States

    5 publications · 549 citations

    5

    h-index

  3. SF
    Sylvia F. Boj

    Hubrecht Institute for Developmental Biology and Stem Cell Research, Netherlands

    4 publications · 259 citations

    4

    h-index

  4. SD
    Steven D. Forsythe

    Wake Forest University, United States

    3 publications · 592 citations

    3

    h-index

  5. JA
    Julio Aleman

    Wake Forest University, United States

    3 publications · 592 citations

    3

    h-index

1–5 of 1.2K

Institutions

335

  1. University Medical Center Utrecht

    Utrecht, The Netherlands

    13 h-index

    73 publications

    8.9K citations

  2. Oncode Institute

    Utrecht, Netherlands

    9 h-index

    39 publications

    3.8K citations

  3. Royal Netherlands Academy of Arts and Sciences

    Amsterdam, The Netherlands

    8 h-index

    33 publications

    3.7K citations

  4. Wake Forest University

    Winston-Salem, United States

    7 h-index

    40 publications

    7K citations

  5. Forest Institute

    Springfield, United States

    6 h-index

    24 publications

    2.9K citations

  6. The University of Melbourne

    Melbourne, Australia

    5 h-index

    16 publications

    951 citations

  7. Utrecht University

    Utrecht, The Netherlands

    5 h-index

    26 publications

    1.5K citations

  8. Keio University

    Tokyo, Japan

    5 h-index

    45 publications

    4.4K citations

1–8 of 335

Venues

  1. Nature Communications

    6 publications · 1.1K citations

    6

    h-index

  2. STAR Protocols

    4 publications · 137 citations

    5

    h-index

  3. Cell stem cell

    5 publications · 657 citations

    5

    h-index

  4. Cell Reports

    4 publications · 436 citations

    4

    h-index

  5. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 4 publications · 164 citations

    4

    h-index

1–5