Concepedia

Mrna Stability Control

mRNA Stability Control is a regulatory mechanism that determines the lifespan of messenger RNA molecules in the cell by modulating their susceptibility to degradation, thereby influencing gene expression dynamics in response to environmental or cellular stresses.

1.8K

Publications

131.8K

Citations

8.4K

Authors

1.8K

Institutions

Publications per year

2017–2026

456

Parents

Publications

1.8K

N6-methyladenosine-dependent regulation of messenger RNA stability

Xiao Wang, Zhike Lu, Adrian Gomez-Nguyen et al. · Nature · 2013 · 4.8K citations

, , +14

Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

Huilin Huang, Hengyou Weng, Wenju Sun et al. · Nature Cell Biology · 2018 · 3.1K citations

, , +16

Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites

Schraga Schwartz, Maxwell R. Mumbach, Marko Jovanović et al. · Cell Reports · 2014 · 1.3K citations · Full text

, , +15

Codon Optimality Is a Major Determinant of mRNA Stability

Vladimir Presnyak, Najwa Alhusaini, Ying-Hsin Chen et al. · Cell · 2015 · 1.1K citations · Full text

, , +16

Genetic compensation triggered by mutant mRNA degradation

Mohamed A. El-Brolosy, Zacharias Kontarakis, Andrea Rossi et al. · Nature · 2019 · 1.1K citations · Full text

, , +14

1–5 of 1.8K

Authors

8.4K

  1. MG
    Myriam Gorospe

    National Institute on Aging, United States

    18 publications · 1.8K citations

    18

    h-index

  2. GB
    Gary Brewer

    Johnson University, United States

    15 publications · 2K citations

    15

    h-index

  3. MK
    Megerditch Kiledjian

    Rutgers, The State University of New Jersey, United States

    13 publications · 1.1K citations

    13

    h-index

  4. XC
    Xinbin Chen

    University of California, Davis, United States

    13 publications · 550 citations

    12

    h-index

  5. PJ
    Perry J. Blackshear

    National Institute of Environmental Health Sciences, United States

    10 publications · 566 citations

    10

    h-index

1–5 of 8.4K

Institutions

1.8K

  1. National Institutes of Health

    Bethesda, United States

    33 h-index

    131 publications

    11.6K citations

  2. Harvard University

    Cambridge, United States

    27 h-index

    119 publications

    14.2K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    27 h-index

    86 publications

    28.9K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    26 h-index

    134 publications

    7.6K citations

  5. Rutgers, The State University of New Jersey

    New Brunswick, United States

    26 h-index

    112 publications

    8.9K citations

  6. Yale University

    New Haven, United States

    25 h-index

    86 publications

    8.9K citations

  7. Sun Yat-sen University

    Guangzhou, China

    23 h-index

    206 publications

    28K citations

  8. University of Pennsylvania

    Philadelphia, United States

    20 h-index

    67 publications

    4.1K citations

1–8 of 1.8K

Venues

  1. Molecular and Cellular Biology

    MCB · 117 publications · 11.4K citations

    63

    h-index

  2. Journal of Biological Chemistry

    JBC · 158 publications · 10.7K citations

    63

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 52 publications · 7.7K citations

    43

    h-index

  4. Nucleic Acids Research

    79 publications · 5.5K citations

    41

    h-index

  5. The Journal of Immunology

    JI · 48 publications · 3.7K citations

    33

    h-index

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