Ying-Hsin Chen

Codon Optimality Is a Major Determinant of mRNA Stability

Vladimir Presnyak, Najwa Alhusaini, Ying-Hsin Chen et al. · Cell · 2015 · 1.1K citations · Full text

Systems Biology, Genetics, Rna Structure Prediction +2

The DEAD-Box Protein Dhh1p Couples mRNA Decay and Translation by Monitoring Codon Optimality

Aditya Radhakrishnan, Ying-Hsin Chen, Sophie Martin et al. · Cell · 2016 · 306 citations · Full text

Protein Biosynthesis, Protein Evolution, Molecular Biology +4

The Ccr4-Not complex monitors the translating ribosome for codon optimality

Robert Buschauer, Yoshitaka Matsuo, Takato Sugiyama et al. · Science · 2020 · 292 citations · Full text

Short poly(A) tails are a conserved feature of highly expressed genes

Sarah Azoubel Lima, Laura B. Chipman, Angela L Nicholson et al. · Nature Structural & Molecular Biology · 2017 · 291 citations

Genetics, Gene Structure, Genomic Mechanism +11

mRNA Deadenylation Is Coupled to Translation Rates by the Differential Activities of Ccr4-Not Nucleases

Michael Webster, Ying-Hsin Chen, James A. W. Stowell et al. · Molecular Cell · 2018 · 253 citations · Full text

Chromatin, Engineering, Natural Sciences +12