Ligand Efficiency Indices is a metric that quantifies the biological activity of a ligand relative to its molecular size or other physicochemical properties, enabling the optimization of binding efficiency in drug discovery.
69
Publications
4.5K
Citations
404
Authors
125
Institutions
Publications per year
2017–2026
24
Variants
Ligand Efficiency Metrics
Publications
69
Ligand efficiency indices as guideposts for drug discovery
C ABADZAPATERO · Drug Discovery Today · 2005 · 523 citations
Ligand efficiency as a guide in fragment hit selection and optimization
Sabine Schultes, Chris de Graaf, Eric Haaksma et al. · Drug Discovery Today Technologies · 2010 · 249 citations · Full text
1–5 of 69
Authors
404
- AT
5
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- UM
4
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- CH
3
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- CA
3
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- IJ
3
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1–5 of 404
Institutions
125
University of Tartu
Tartu, Estonia
6 h-index
17 publications
787 citations
European Bioinformatics Institute
Cambridge, United Kingdom
3 h-index
10 publications
1.3K citations
University of Illinois Chicago
Chicago, United States
3 h-index
5 publications
639 citations
AstraZeneca (United Kingdom)
Cambridge, United Kingdom
3 h-index
21 publications
1.1K citations
GlaxoSmithKline (Ireland)
Cork, Ireland
2 h-index
3 publications
417 citations
Center for Genomic Science
Milan, Italy
2 h-index
6 publications
250 citations
Chugai Pharma (United States)
Berkeley Heights, United States
2 h-index
2 publications
37 citations
University of Silesia in Katowice
Katowice, Poland
2 h-index
5 publications
81 citations
1–8 of 125
Venues
- Journal of Medicinal Chemistry
13 publications · 1.2K citations
13
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- Journal of Chemical Information and Modeling
JCIM · 11 publications · 410 citations
11
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- ACS Medicinal Chemistry Letters
5 publications · 416 citations
5
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- Bioorganic & Medicinal Chemistry
3 publications · 117 citations
3
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- Molecules
2 publications · 100 citations
2
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1–5