Charles H. Reynolds

Ligand Binding Efficiency: Trends, Physical Basis, and Implications

Charles H. Reynolds, Brett A. Tounge, Scott D. Bembenek · Journal of Medicinal Chemistry · 2008 · 318 citations

Pharmacy, Medicinal Chemistry, Computational Chemistry +15

An improved set of mndo parameters for sulfur

Michael J. S. Dewar, Charles H. Reynolds · Journal of Computational Chemistry · 1986 · 247 citations

Natural Sciences, Chemistry, Computational Chemistry +4

Discovery of 2-[3,5-Dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β Agonist in Clinical Trials for the Treatment of Dyslipidemia

Martha J. Kelly, Sherrie Pietranico-Cole, J. Douglas Larigan et al. · Journal of Medicinal Chemistry · 2014 · 215 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Performance of Similarity Measures in 2D Fragment-Based Similarity Searching:  Comparison of Structural Descriptors and Similarity Coefficients

Xin Chen, Charles H. Reynolds · Journal of Chemical Information and Computer Sciences · 2002 · 200 citations

Pharmacy, Chemistry, Medicinal Chemistry +17

Breakpoints of the t(11;18)(q21;q21) in mucosa-associated lymphoid tissue (MALT) lymphoma lie within or near the previously undescribed gene MALT1 in chromosome 18.

James P. Morgan, Alexander D. Borowsky, Frank C. Kuo et al. · PubMed · 1999 · 172 citations

Life Sciences, Genetics, Oncology +16