J. Douglas Larigan

Discovery of 2-[3,5-Dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β Agonist in Clinical Trials for the Treatment of Dyslipidemia

Martha J. Kelly, Sherrie Pietranico-Cole, J. Douglas Larigan et al. · Journal of Medicinal Chemistry · 2014 · 205 citations · Full text

Pharmacotherapy, Experimental Pharmacology, Central Thyroid Axis +16

Characterization of site-directed mutants in the lac permease of Escherichia coli. 2. Glutamate-325 replacements

Nancy Carrasco, Irene B. Puttner, Lisa M. Antes et al. · Biochemistry · 1989 · 94 citations · Full text

Lac Permease, Bacteriology, Molecular Biology +18

The 37/40-kilodalton autoantigen in insulin-dependent diabetes mellitus is the putative tyrosine phosphatase IA-2.

Nadia Passini, J. Douglas Larigan, Stefano Genovese et al. · Proceedings of the National Academy of Sciences · 1995 · 72 citations · Full text

Immunology, Antigen Processing, Insulin Signaling +23

A Sense Phosphorothioate Oligonucleotide Directed to the Initiation Codon of Transcription Factor NF-κ-B Causes Sequence-Specific Immune Stimulation

Kim W. McIntyre, KATHLEEN LOMBARD-GILLOOLY, José R. Perez et al. · Antisense Research and Development · 1993 · 63 citations

Functional contributions of the FcεRIα and FεRIγ subunit domains in FcεRI-mediated signaling in mast cells

Barbara Repetto, Geethani Bandara, Helen Kado‐Fong et al. · The Journal of Immunology · 1996 · 25 citations