Concepedia

Immune Tolerance

Immune Tolerance is a fundamental immunological state in which the immune system specifically fails to mount or sustain effector responses against self-antigens or selected innocuous antigens while preserving its capacity to respond effectively to other foreign antigens.

2.3K

Publications

179.6K

Citations

7.8K

Authors

1.6K

Institutions

Publications per year

2017–2026

136

Parents

Children

Publications

2.3K

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

Shimon Sakaguchi, N Sakaguchi, M Asano et al. · The Journal of Immunology · 1995 · 5.5K citations

, , +17

‘Actively Acquired Tolerance’ of Foreign Cells

R. E. Billingham, L Brent, P. B. Medawar · Nature · 1953 · 3.1K citations

, , +14

T cell tolerance by clonal elimination in the thymus

John W. Kappler, Neal W. Roehm, Philippa Marrack · Cell · 1987 · 2.2K citations

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Dendritic Cells Induce Peripheral T Cell Unresponsiveness under Steady State Conditions in Vivo

Daniel Hawiger, Kayo Inaba, Yair Dorsett et al. · The Journal of Experimental Medicine · 2001 · 1.8K citations · Full text

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Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance

Jun Shimizu, Sayuri Yamazaki, Takeshi Takahashi et al. · Nature Immunology · 2002 · 1.7K citations

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1–5 of 2.3K

Authors

7.8K

  1. HW
    Herman Waldmann

    University of Oxford, United Kingdom

    35 publications · 4.9K citations

    28

    h-index

  2. SC
    Stephen Cobbold

    University of Cambridge, United Kingdom

    25 publications · 4.2K citations

    23

    h-index

  3. SD
    Stephen D. Miller

    Northwestern University, United States

    27 publications · 2.3K citations

    21

    h-index

  4. WO
    William O. Weigle

    Scripps Health, United States

    30 publications · 1.8K citations

    21

    h-index

  5. BB
    Baruj Benacerraf

    Harvard University, United States

    22 publications · 1.2K citations

    19

    h-index

1–5 of 7.8K

Institutions

1.6K

  1. Harvard University

    Cambridge, United States

    54 h-index

    393 publications

    39.5K citations

  2. National Institutes of Health

    Bethesda, United States

    37 h-index

    175 publications

    17.1K citations

  3. Brigham and Women's Hospital

    Boston, United States

    35 h-index

    149 publications

    18K citations

  4. Inserm

    Paris, France

    34 h-index

    183 publications

    17.1K citations

  5. Walter and Eliza Hall Institute of Medical Research

    Melbourne, Australia

    30 h-index

    139 publications

    14.6K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    30 h-index

    89 publications

    19.6K citations

  7. University of Colorado Denver

    Denver, United States

    30 h-index

    112 publications

    15.4K citations

  8. Massachusetts General Hospital

    Boston, United States

    29 h-index

    179 publications

    11.7K citations

1–8 of 1.6K

Venues

  1. The Journal of Immunology

    JI · 374 publications · 30K citations

    83

    h-index

  2. The Journal of Experimental Medicine

    190 publications · 23.3K citations

    83

    h-index

  3. PubMed

    Repository · 235 publications · 9.8K citations

    47

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 66 publications · 7.1K citations

    42

    h-index

  5. Nature

    74 publications · 13.6K citations

    41

    h-index

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