Concepedia

B-cell Tolerance

B-Cell Tolerance is a biological mechanism within the immune system that prevents B cells from producing antibodies against self-antigens, thereby maintaining immune tolerance through the elimination or inactivation of autoreactive B-cell clones.

565

Publications

39.6K

Citations

2.5K

Authors

637

Institutions

Publications per year

2017–2026

54

Parents

Publications

565

The Influence of Antigen Organization on B Cell Responsiveness

Martin F. Bachmann, Urs Hoffmann Rohrer, Thomas M. Kündig et al. · Science · 1993 · 731 citations

, , +17

Baff Mediates Survival of Peripheral Immature B Lymphocytes

Marcel Batten, Joanna R. Groom, Teresa G. Cachero et al. · The Journal of Experimental Medicine · 2000 · 704 citations · Full text

, , +17

Defective B cell tolerance checkpoints in systemic lupus erythematosus

Sergey Yurasov, Hedda Wardemann, Johanna Hammersen et al. · The Journal of Experimental Medicine · 2005 · 700 citations · Full text

, , +17

B Cells Turn Off Virgin But Not Memory T Cells

Ephraim J. Fuchs, Polly Matzinger · Science · 1992 · 570 citations · Full text

, , +17

Metabolic Reprogramming Is Required for Antibody Production That Is Suppressed in Anergic but Exaggerated in Chronically BAFF-Exposed B Cells

Alfredo Caro‐Maldonado, Ruoning Wang, Amanda Nichols et al. · The Journal of Immunology · 2014 · 551 citations · Full text

, , +17

1–5 of 565

Authors

2.5K

  1. EM
    Eric Meffre

    Yale University, United States

    25 publications · 3.5K citations

    23

    h-index

  2. DN
    David Nemazee

    Scripps Research Institute, United States

    20 publications · 1.7K citations

    18

    h-index

  3. DW
    David W. Scott

    Duke University, United States

    26 publications · 924 citations

    18

    h-index

  4. BD
    Betty Diamond

    Feinstein Institute for Medical Research, United States

    17 publications · 2K citations

    15

    h-index

  5. CC
    Christopher C. Goodnow

    Australian National University, Australia

    16 publications · 1.9K citations

    15

    h-index

1–5 of 2.5K

Institutions

637

  1. Yale University

    New Haven, United States

    29 h-index

    149 publications

    11.9K citations

  2. University of Colorado Denver

    Denver, United States

    24 h-index

    123 publications

    7.7K citations

  3. Harvard University

    Cambridge, United States

    24 h-index

    115 publications

    7.9K citations

  4. University of Pennsylvania

    Philadelphia, United States

    23 h-index

    95 publications

    5K citations

  5. National Jewish Health

    Denver, United States

    22 h-index

    93 publications

    6.6K citations

  6. National Institutes of Health

    Bethesda, United States

    17 h-index

    35 publications

    3.1K citations

  7. Scripps Research Institute

    San Diego, United States

    17 h-index

    98 publications

    6.6K citations

  8. The University of Texas Southwestern Medical Center

    Dallas, United States

    16 h-index

    50 publications

    4K citations

1–8 of 637

Venues

  1. The Journal of Immunology

    JI · 155 publications · 8.7K citations

    50

    h-index

  2. The Journal of Experimental Medicine

    74 publications · 8.7K citations

    46

    h-index

  3. European Journal of Immunology

    EJI · 50 publications · 1.9K citations

    26

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 21 publications · 1.5K citations

    19

    h-index

  5. Journal of Clinical Investigation

    JCI · 18 publications · 3.1K citations

    18

    h-index

1–5