Concepedia

Immunological Ignorance

Immunological Ignorance is a mechanism of peripheral tolerance in which self-reactive T cells remain functionally unresponsive to tissue-specific antigens due to the physical sequestration of those antigens from the immune system, rather than through active suppression or deletion.

34

Publications

2.5K

Citations

145

Authors

66

Institutions

Publications per year

2017–2026

4

Parents

Publications

34

Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism

Emma Slack, Siegfried Hapfelmeier, Bärbel Stecher et al. · Science · 2009 · 502 citations · Full text

, , +17

Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors

Ryan A. Wilcox, Dallas B. Flies, Gefeng Zhu et al. · Journal of Clinical Investigation · 2002 · 260 citations · Full text

, , +17

CD8 T cell ignorance or tolerance to islet antigens depends on antigen dose

Christian Kurts, Robyn M. Sutherland, Gayle M. Davey et al. · Proceedings of the National Academy of Sciences · 1999 · 242 citations

, , +17

Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors

Ryan A. Wilcox, Dallas B. Flies, Gefeng Zhu et al. · Journal of Clinical Investigation · 2002 · 219 citations · Full text

, , +17

The Croonian Lecture: The homograft reaction

Peter Medawar · Proceedings of the Royal Society of London. Series B, Biological sciences · 1958 · 135 citations

, , +10

1–5 of 34

Authors

145

  1. LC
    Lieping Chen

    Yale University, United States

    4 publications · 582 citations

    4

    h-index

  2. AJ
    Aaron J. Johnson

    Mayo Clinic, United States

    3 publications · 493 citations

    3

    h-index

  3. SE
    Scott E. Strome

    University of Maryland, Baltimore, United States

    3 publications · 493 citations

    3

    h-index

  4. RA
    Ryan A. Wilcox

    University of Michigan, United States

    3 publications · 493 citations

    3

    h-index

  5. DB
    Dallas B. Flies

    Mayo Clinic, United States

    3 publications · 493 citations

    3

    h-index

1–5 of 145

Institutions

66

  1. Mayo Clinic

    Rochester, United States

    3 h-index

    10 publications

    2.3K citations

  2. Duke Medical Center

    Durham, United States

    2 h-index

    4 publications

    652 citations

  3. WinnMed

    Decorah, United States

    2 h-index

    2 publications

    233 citations

  4. Duke University Hospital

    Durham, United States

    2 h-index

    4 publications

    652 citations

  5. Eastern Hepatobiliary Surgery Hospital

    Shanghai, China

    2 h-index

    2 publications

    233 citations

  6. Second Military Medical University

    Shanghai, China

    2 h-index

    2 publications

    233 citations

  7. Emory University

    Atlanta, United States

    2 h-index

    5 publications

    58 citations

  8. Seoul National University Hospital

    Seoul, South Korea

    1 h-index

    1 publications

    28 citations

1–8 of 66

Venues

  1. The Journal of Immunology

    JI · 4 publications · 181 citations

    4

    h-index

  2. Journal of Clinical Investigation

    JCI · 4 publications · 560 citations

    4

    h-index

  3. PubMed

    Repository · 3 publications · 186 citations

    3

    h-index

  4. Perspectives in biology and medicine

    2 publications · 59 citations

    2

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 254 citations

    2

    h-index

1–5