Concepedia

Immune Cell Differentiation

Immune Cell Differentiation is a cellular developmental process in which hematopoietic stem and progenitor cells progressively commit to and acquire the stable phenotypic, functional, and molecular characteristics of distinct immune cell lineages under the control of specific transcriptional programs and extrinsic cues such as cytokines and microenvironmental signals.

9.6K

Publications

874K

Citations

42K

Authors

4.6K

Institutions

Publications per year

2017–2026

1.4K

Parents

Children

Publications

9.6K

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Jason D. Fontenot, Marc A. Gavin, Alexander Y. Rudensky · Nature Immunology · 2003 · 7.7K citations

, , +14

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Estelle Bettelli, Yijun Carrier, Wenda Gao et al. · Nature · 2006 · 6.9K citations

, , +16

The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

Ivaylo I. Ivanov, Brent S. McKenzie, Liang Zhou et al. · Cell · 2006 · 5.1K citations · Full text

, , +16

Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

Laurie E. Harrington, Robin D. Hatton, Paul R. Mangan et al. · Nature Immunology · 2005 · 4.7K citations

, , +17

Human mesenchymal stem cells modulate allogeneic immune cell responses

Sudeepta Aggarwal, Mark F. Pittenger · Blood · 2004 · 4.5K citations · Full text

, , +13

1–5 of 9.6K

Authors

42K

  1. IL
    Irving L. Weissman

    Stanford University, United States

    43 publications · 10.9K citations

    38

    h-index

  2. KS
    Ken Shortman

    Walter and Eliza Hall Institute of Medical Research, Australia

    47 publications · 8.1K citations

    36

    h-index

  3. HS
    Hergen Spits

    University of Amsterdam, Netherlands

    44 publications · 5K citations

    34

    h-index

  4. HR
    H. Robson MacDonald

    Ludwig Cancer Research, Switzerland

    36 publications · 5.3K citations

    31

    h-index

  5. FG
    Florent Ginhoux

    Singapore Immunology Network, Singapore

    35 publications · 8.1K citations

    30

    h-index

1–5 of 42K

Institutions

4.6K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    130 h-index

    786 publications

    213K citations

  2. Inserm

    Paris, France

    112 h-index

    2.2K publications

    235.4K citations

  3. National Institutes of Health

    Bethesda, United States

    111 h-index

    1.5K publications

    211.6K citations

  4. Harvard University

    Cambridge, United States

    106 h-index

    1.2K publications

    217.6K citations

  5. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    82 h-index

    644 publications

    76.7K citations

  6. National Cancer Institute

    Bethesda, United States

    77 h-index

    718 publications

    96K citations

  7. Stanford University

    Stanford, United States

    77 h-index

    564 publications

    98.1K citations

  8. Walter and Eliza Hall Institute of Medical Research

    Melbourne, Australia

    76 h-index

    772 publications

    98.3K citations

1–8 of 4.6K

Venues

  1. The Journal of Immunology

    JI · 1.5K publications · 131.2K citations

    169

    h-index

  2. Blood

    811 publications · 92.8K citations

    162

    h-index

  3. The Journal of Experimental Medicine

    476 publications · 82.2K citations

    158

    h-index

  4. Immunity

    201 publications · 58.4K citations

    126

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 274 publications · 38.3K citations

    103

    h-index

1–5