Concepedia

Clonal Evolution

Clonal Evolution is a biological process in cancer development whereby genetically distinct subclones arise within a tumor due to the accumulation of somatic mutations and selective pressures, leading to dynamic changes in clonal composition over time.

1.2K

Publications

146.6K

Citations

8.7K

Authors

1.8K

Institutions

Publications per year

2017–2026

385

Parents

Children

Publications

1.2K

The Clonal Evolution of Tumor Cell Populations

Peter C. Nowell̀ · Science · 1976 · 6.5K citations

, , +17

Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes

Siddhartha Jaiswal, Pierre Fontanillas, Jason Flannick et al. · New England Journal of Medicine · 2014 · 4.7K citations · Full text

, , +17

Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence

Giulio Genovese, Anna K. Kähler, Robert E. Handsaker et al. · New England Journal of Medicine · 2014 · 3.5K citations · Full text

, , +16

Tracking the Evolution of Non–Small-Cell Lung Cancer

Mariam Jamal‐Hanjani, Gareth A. Wilson, Nicholas McGranahan et al. · New England Journal of Medicine · 2017 · 2.4K citations · Full text

, , +17

The clonal and mutational evolution spectrum of primary triple-negative breast cancers

Sohrab P. Shah, Andrew Roth, Rodrigo Goya et al. · Nature · 2012 · 2K citations

, , +14

1–5 of 1.2K

Authors

8.7K

  1. TA
    Trevor A. Graham

    Queen Mary University of London, United Kingdom

    21 publications · 2.4K citations

    18

    h-index

  2. PJ
    Peter J. Campbell

    Wellcome Sanger Institute, United Kingdom

    18 publications · 6.2K citations

    17

    h-index

  3. AS
    Andrea Sottoriva

    Institute of Cancer Research, United Kingdom

    17 publications · 1.9K citations

    15

    h-index

  4. NB
    Niko Beerenwinkel

    ETH Zurich, Switzerland

    17 publications · 2.1K citations

    15

    h-index

  5. SO
    Seishi Ogawa

    The University of Tokyo, Japan

    14 publications · 2.4K citations

    14

    h-index

1–5 of 8.7K

Institutions

1.8K

  1. Harvard University

    Cambridge, United States

    48 h-index

    252 publications

    70.2K citations

  2. University of Cambridge

    Cambridge, United Kingdom

    43 h-index

    214 publications

    48.9K citations

  3. University College London

    London, United Kingdom

    35 h-index

    259 publications

    227.9K citations

  4. Dana-Farber Cancer Institute

    Boston, United States

    34 h-index

    196 publications

    66.9K citations

  5. Memorial Sloan Kettering Cancer Center

    New York, United States

    33 h-index

    257 publications

    74.8K citations

  6. Institute of Cancer Research

    London, United Kingdom

    32 h-index

    225 publications

    38.5K citations

  7. University of Washington

    Seattle, United States

    29 h-index

    128 publications

    24K citations

  8. Wellcome Sanger Institute

    Cambridge, United Kingdom

    29 h-index

    265 publications

    77.8K citations

1–8 of 1.8K

Venues

  1. Blood

    64 publications · 6.3K citations

    43

    h-index

  2. Nature Communications

    51 publications · 6.9K citations

    40

    h-index

  3. PubMed

    Repository · 82 publications · 5.8K citations

    39

    h-index

  4. Nature

    40 publications · 16.6K citations

    38

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 37 publications · 8.5K citations

    32

    h-index

1–5