Concepedia

Aneuploidy Evolution

Aneuploidy Evolution is a theoretical framework within the study of clonal evolution that specifically characterizes the dynamic acquisition and selection of chromosomal imbalances during tumor progression, distinguishing itself by focusing on the role of aneuploid karyotypes as drivers of intratumoral heterogeneity and adaptive evolution.

109

Publications

7K

Citations

563

Authors

232

Institutions

Publications per year

2017–2026

28

Parents

Publications

109

The role of chromosomal instability in tumor initiation

Martin A. Nowak, Natalia L. Komarova, Anirvan M. Sengupta et al. · Proceedings of the National Academy of Sciences · 2002 · 544 citations · Full text

, , +17

Chromosomal duplication is a transient evolutionary solution to stress

Avihu H. Yona, Yair S. Manor, Rebecca H. Herbst et al. · Proceedings of the National Academy of Sciences · 2012 · 398 citations · Full text

, , +15

Aneuploidy Underlies Rapid Adaptive Evolution of Yeast Cells Deprived of a Conserved Cytokinesis Motor

Giulia Rancati, Norman Pavelka, Brian Fleharty et al. · Cell · 2008 · 364 citations · Full text

, , +14

Model for the genetic evolution of human solid tumors.

Stanley E. Shackney, Christina Smith, Brent W. Miller et al. · PubMed · 1989 · 255 citations

, , +17

Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids

Ana C.F. Bolhaqueiro, Bas Ponsioen, Björn Bakker et al. · Nature Genetics · 2019 · 244 citations · Full text

, , +16

1–5 of 109

Authors

563

  1. SE
    Stanley E. Shackney

    Allegheny General Hospital, United States

    5 publications · 451 citations

    5

    h-index

  2. KS
    Kate Swift

    University of Tasmania, Australia

    3 publications · 175 citations

    3

    h-index

  3. JM
    Jason M. Sheltzer

    Cold Spring Harbor Laboratory, United States

    3 publications · 479 citations

    3

    h-index

  4. AP
    Anne‐Maree Pearse

    The University of Sydney, Australia

    3 publications · 175 citations

    3

    h-index

  5. FM
    Felix Mitelman

    Lund University, Sweden

    3 publications · 101 citations

    3

    h-index

1–5 of 563

Institutions

232

  1. Lund University

    Lund, Sweden

    8 h-index

    24 publications

    802 citations

  2. Harvard University

    Cambridge, United States

    5 h-index

    25 publications

    1.4K citations

  3. Tel Aviv University

    Tel Aviv, Israel

    4 h-index

    15 publications

    1.4K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    16 publications

    959 citations

  5. University of Kaiserslautern

    Kaiserslautern, Germany

    4 h-index

    9 publications

    1.2K citations

  6. Institute of Cancer Research

    London, United Kingdom

    4 h-index

    22 publications

    713 citations

  7. University of Michigan

    Ann Arbor, United States

    4 h-index

    11 publications

    732 citations

  8. Johns Hopkins University

    Baltimore, United States

    4 h-index

    12 publications

    4K citations

1–8 of 232

Venues

  1. Cancer Genetics and Cytogenetics

    7 publications · 420 citations

    7

    h-index

  2. PubMed

    Repository · 6 publications · 441 citations

    6

    h-index

  3. Genes Chromosomes and Cancer

    5 publications · 153 citations

    5

    h-index

  4. Cytometry

    4 publications · 196 citations

    4

    h-index

  5. Hereditas

    4 publications · 186 citations

    4

    h-index

1–5