Precision Oncology

Precision oncology is a therapeutic approach to cancer treatment that individualizes pharmacologic intervention through molecular and genetic profiling of patient and tumor characteristics to predict treatment response and optimize clinical outcomes.

4.5K

Publications

349.7K

Citations

36.5K

Authors

5.4K

Institutions

Publications per year

2017–2026

2.9K

Variants

Precision Cancer Medicine

Parents

Oncology Pharmacy

Children

Biomarker DiscoveryCancer GenomicsCirculating Tumor Dna AnalysisClonal EvolutionCompanion DiagnosticsEpigenomic ProfilingGermline Cancer PredispositionImmuno-oncology BiomarkersLiquid BiopsyMinimal Residual Disease

Publications

4.5K

A Multigene Assay to Predict Recurrence of Tamoxifen-Treated, Node-Negative Breast Cancer

Soonmyung Paik, Steven Shak, Gong Tang et al. · New England Journal of Medicine · 2004 · 6.4K citations · Full text

Medicine, Oncology, Breast Oncology +12

ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking

Matthew D. Wilkerson, D. Neil Hayes · Bioinformatics · 2010 · 6.3K citations · Full text

Life Sciences, Bioinformatics, Oncology +11

Pembrolizumab for the Treatment of Non–Small-Cell Lung Cancer

Edward B. Garon, Naiyer A. Rizvi, Rina Hui et al. · New England Journal of Medicine · 2015 · 6.2K citations · Full text

Medicine, Oncology, Pharmacology +17

Osimertinib in Untreated <i>EGFR</i> -Mutated Advanced Non–Small-Cell Lung Cancer

Jean‐Charles Soria, Yuichiro Ohe, Johan Vansteenkiste et al. · New England Journal of Medicine · 2017 · 5.3K citations · Full text

Medicine, Oncology, Pharmacology +16

A New Initiative on Precision Medicine

Francis S. Collins, Harold Varmus · New England Journal of Medicine · 2015 · 5.2K citations · Full text

Medicine, Biomedical Sciences, Oncology +15

1–5 of 4.5K

Authors

36.5K

JT
Josep Tabernero
Vall d'Hebron Hospital Universitari, Spain
59 publications · 7.1K citations
33
h-index
RK
Razelle Kurzrock
The University of Texas MD Anderson Cancer Center, United States
47 publications · 4.3K citations
31
h-index
EV
Eric Van Cutsem
KU Leuven, Belgium
52 publications · 12.4K citations
31
h-index
FM
Funda Meric‐Bernstam
The University of Texas MD Anderson Cancer Center, United States
33 publications · 10.4K citations
27
h-index
RJ
Robert J. Motzer
Memorial Sloan Kettering Cancer Center, United States
33 publications · 2.8K citations
26
h-index

1–5 of 36.5K

Institutions

5.4K

1–8 of 5.4K

Venues

Journal of Clinical Oncology
625 publications · 48.7K citations
100
h-index
Clinical Cancer Research
159 publications · 22.3K citations
71
h-index
Annals of Oncology
115 publications · 11K citations
52
h-index
Nature Communications
69 publications · 8.4K citations
44
h-index
Cancer Discovery
45 publications · 14.8K citations
35
h-index

1–5

See also Precision Oncology
Therapy Selection	Predictive Biomarkers Companion Diagnostics Compound-target Interaction Prediction Response Prediction Models
Biomarkers	Egfr Mutation Testing Epigenetic Biomarkers Brca Mutations Drug Resistance Biomarkers Braf V600e Mutation
Profiling Technologies	Rna Sequencing Next-generation Sequencing Genome Sequencing Whole Exome Sequencing Studies Dna Methylation Profiling Cancer Gene Panel Sequencing Immunohistochemistry Proteomic Profiling Metabolomics
Clinical Trials	Patient Stratification Adaptive Platform Trial Design Multi-arm Multi-stage Design Hierarchical Bayesian Estimation
Implementation Challenges	Standardization Of Biomarker Assays Explainable Artificial Intelligence Multicenter Validation Data Privacy Clinical Decision Support Systems Molecular Tumor Profiling Genomic Literacy In Families Algorithmic Bias Healthcare Interoperability Resources Reimbursement Policy