Biomarker discovery is **biomarker discovery is** the research field dedicated to identifying and validating biological characteristics that serve as objectively measurable indicators of normal biological or pathological processes, or responses to therapeutic interventions. This systematic process employs high-throughput technologies such as genomics, proteomics, and metabolomics to find potential molecular or cellular markers, followed by rigorous validation studies to confirm their clinical utility and significance in diagnostics, prognostics, or therapeutic development.