Precision Medicine

Precision medicine is a clinical methodology that customizes therapeutic and preventive interventions through integrated analysis of individual genomic, environmental, and lifestyle characteristics to enable targeted treatment selection and risk stratification.

7.4K

Publications

443.3K

Citations

54.9K

Authors

8.3K

Institutions

Publications per year

2017–2026

4.7K

Variants

Personalized Medicine

Parents

Molecular MedicineTranslational Sciences

Children

Biomarker DiscoveryCancer Precision MedicineClinical GenomicsCompanion DiagnosticsDisease SubtypingGenomic ProfilingGermline Variant InterpretationImmunogenomicsLiquid BiopsyMutation Analysis

Publications

7.4K

A New Initiative on Precision Medicine

Francis S. Collins, Harold Varmus · New England Journal of Medicine · 2015 · 5.2K citations · Full text

Medicine, Biomedical Sciences, Oncology +15

X-Tile

Robert L. Camp, Marisa Dolled‐Filhart, David L. Rimm · Clinical Cancer Research · 2004 · 3.9K citations

Medicine, Biostatistics, Oncology +17

DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants

Janet Piñero, Álex Bravo, Núria Queralt-Rosiñach et al. · Nucleic Acids Research · 2016 · 2.8K citations · Full text

Life Sciences, Bioinformatics, Genetics +17

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

Daniel Taliun, Daniel Harris, Michael D. Kessler et al. · Nature · 2021 · 2.3K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer

Fátima Cardoso, Laura J. van’t Veer, Jan Bogaerts et al. · New England Journal of Medicine · 2016 · 2.1K citations · Full text

Medicine, Genetics, Oncology +16

1–5 of 7.4K

Authors

54.9K

RK
Razelle Kurzrock
The University of Texas MD Anderson Cancer Center, United States
35 publications · 4K citations
28
h-index
FS
Fred S. Apple
Hennepin County Medical Center, United States
21 publications · 2.6K citations
20
h-index
FA
Fabrice André
Institut Gustave Roussy, France
20 publications · 3.8K citations
19
h-index
FM
Funda Meric‐Bernstam
The University of Texas MD Anderson Cancer Center, United States
19 publications · 3.2K citations
19
h-index
AM
Apostolia M. Tsimberidou
The University of Texas MD Anderson Cancer Center, United States
18 publications · 2.2K citations
17
h-index

1–5 of 54.9K

Institutions

8.3K

1–8 of 8.3K

Venues

Nature Communications
86 publications · 10.1K citations
50
h-index
Clinical Chemistry
105 publications · 8.7K citations
47
h-index
Clinical Cancer Research
70 publications · 10.4K citations
43
h-index
Scientific Reports
123 publications · 7.3K citations
42
h-index
PubMed
Repository · 183 publications · 6.6K citations
38
h-index

1–5

See also Precision Medicine
Core Methods	Bioinformatics Pharmacogenomics Machine Learning Deep Learning Metabolomics Genome Sequencing Digital Twin Modeling Biomarker-driven Patient Stratification Drug Response Modeling Biomarker-driven Clinical Trial Design
Applications	Pharmacogenomics Drug Repurposing Targeted Cancer Therapy Non-small Cell Lung Cancer Treatment Breast Cancer Risk Models Biological Prognosis Non-invasive Prenatal Testing Type 1 Diabetes Hyperglycemia Management Model Surgery Simulation Follow-up Care Plans
Data Sources	Genomics Metabolomics Medical Imaging Electronic Health Records Proteomics Transcriptomics Health Data Monitoring Wearable Health Devices Biological Sample Repositories
Evaluation	Health Technology Assessment Analytical Validity Randomized Controlled Trials Cost-effectiveness Analysis Quality-adjusted Life Years Biomarker Validation Patient Outcome Monitoring
Limitations	Data Integration Data Standardization Data Interoperability Genomic Data Privacy Health Care Access Disparities Data Harmonization Reimbursement Policy Data Interpretation Cell-state Heterogeneity