Pharmacogenomics

Pharmacogenomics is a scientific discipline that investigates how genetic variants in individuals influence medication response, thereby enabling personalized drug therapy optimized for therapeutic efficacy and safety.

11.7K

Publications

680.9K

Citations

57.8K

Authors

8.1K

Institutions

Publications per year

2017–2026

2.9K

Variants

Pharmacogenomic Sciences

Parents

Molecular MedicinePharmaceutical BiotechnologyPharmacologyPharmacotherapyTranslational Sciences

Children

Allele NomenclatureCancer PharmacogenomicsCardiovascular PharmacogenomicsClinical Implementation Of PharmacogenomicsDrug Metabolism GenomicsDrug ResponseDrug-metabolizing EnzymesEthical Issues In PharmacogenomicsGene - Drug InteractionsGenetic Variation

Publications

11.7K

DrugBank 5.0: a major update to the DrugBank database for 2018

David S. Wishart, Yannick Djoumbou-Feunang, An Chi Guo et al. · Nucleic Acids Research · 2017 · 8.8K citations · Full text

Medicine, Pharmacology, Drug Information +13

Next-generation genotype imputation service and methods

Sayantan Das, Lukas Forer, Sebastian Schönherr et al. · Nature Genetics · 2016 · 4.4K citations · Full text

Life Sciences, Biostatistics, Genetics +10

DrugBank: a knowledgebase for drugs, drug actions and drug targets

David S. Wishart, Craig Knox, An Chi Guo et al. · Nucleic Acids Research · 2007 · 2.9K citations · Full text

Medicine, Bioinformatics, Pharmacology +14

A "Silent" Polymorphism in the <i>MDR</i> 1 Gene Changes Substrate Specificity

Chava Kimchi‐Sarfaty, Jung Mi Oh, In‐Wha Kim et al. · Science · 2006 · 2.5K citations · Full text

Medicine, Genetics, Molecular Genetics +15

Cytochrome P-450 Polymorphisms and Response to Clopidogrel

Jessica L. Mega, Sandra Close, Stephen D. Wiviott et al. · New England Journal of Medicine · 2008 · 2.5K citations · Full text

Medicine, Cardiology, Pharmacology +17

1–5 of 11.7K

Authors

57.8K

TE
Teri E. Klein
Stanford University, United States
103 publications · 25.4K citations
72
h-index
HL
Howard L. McLeod
Washington University in St. Louis, United States
87 publications · 9.6K citations
45
h-index
MS
Matthias Schwab
Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Germany
70 publications · 9.5K citations
45
h-index
JA
Julie A. Johnson
University of Florida, United States
99 publications · 8.4K citations
45
h-index
AG
Andrea Gaedigk
Children's Mercy Hospital, United States
74 publications · 11.5K citations
44
h-index

1–5 of 57.8K

Institutions

8.1K

1–8 of 8.1K

Venues

Clinical Pharmacology & Therapeutics
CPT · 456 publications · 62.2K citations
143
h-index
Pharmacogenetics and Genomics
367 publications · 21.2K citations
79
h-index
The Pharmacogenomics Journal
331 publications · 17.6K citations
69
h-index
Pharmacogenetics
120 publications · 14.9K citations
69
h-index
Pharmacogenomics
566 publications · 21.7K citations
66
h-index

1–5

See also Pharmacogenomics
Genetic Variants	Drug-metabolizing Enzymes Haplotype Analysis Molecular Targets Of Drugs Noncoding Variants
Clinical Applications	Warfarin Dose Optimization Pharmacogenomic Clinical Decision Support
Core Methods	Genome Sequencing Machine Learning Long-read Sequencing Exome Sequencing Combinatorial Optimization Short-read Sequencing Variant Phasing Copy Number Variation Detection Variant Annotation Targeted Sequencing
Implementation	Clinical Decision Support Systems Electronic Health Record Integration Gene-drug Interaction Counseling Personal Health Records Interoperability Medication Risk Identification
Guidelines	Pharmacogenetics