A "Silent" Polymorphism in the <i>MDR</i> 1 Gene Changes Substrate Specificity

Chava Kimchi‐Sarfaty, Jung Mi Oh, In‐Wha Kim, +4

Science

Erlotinib (Tarceva, OSI-774) Antagonizes ATP-Binding Cassette Subfamily B Member 1 and ATP-Binding Cassette Subfamily G Member 2–Mediated Drug Resistance

Zhi Shi, Xing-Xiang Peng, In‐Wha Kim, +9

Cancer Research

Drug TargetMolecular BiologyCancer BiologyTumor BiologyDrug Resistance +15

Modulatory Properties of Various Natural Chemopreventive Agents on the Activation of NF-κB Signaling Pathway

Woo‐Sik Jeong, In‐Wha Kim, Rong Hu, +1

Pharmaceutical Research

InflammationSignal TransductionSignaling PathwayChemoprevention StrategyMedicine +9

Sildenafil Reverses ABCB1- and ABCG2-Mediated Chemotherapeutic Drug Resistance

Zhi Shi, Amit K. Tiwari, Suneet Shukla, +10

Cancer Research

Erectile DysfunctionCellular PharmacologyPharmacotherapyExperimental PharmacologyTranslational Pharmacology +17

Lung-Specific Delivery of Paclitaxel by Chitosan-Modified PLGA Nanoparticles Via Transient Formation of Microaggregates

Rui Yang, Su‐Geun Yang, Won‐Sik Shim, +6

Journal of Pharmaceutical Sciences

NanoparticlesNanomedicineLung-specific DeliveryEngineeringPolymer-drug Conjugate +4

P-Glycoprotein–Mediated Transport of Berberine across Caco-2 Cell Monolayers

Han‐Joo Maeng, Ho-Jung Yoo, In‐Wha Kim, +3

Journal of Pharmaceutical Sciences

P-glycoprotein–mediated TransportBiochemistryNatural SciencesMembrane TransportGlycobiology +6

Catalytic Cycle of ATP Hydrolysis by P-Glycoprotein:  Evidence for Formation of the E·S Reaction Intermediate with ATP-γ-S, a Nonhydrolyzable Analogue of ATP

Zuben E. Sauna, In‐Wha Kim, Krishnamachary Nandigama, +3

Biochemistry

Ethnicity-Related Polymorphisms and Haplotypes in the Human<i>ABCB1</i>Gene

Chava Kimchi‐Sarfaty, Andrew Marple, Shiri Shinar, +9

Pharmacogenomics

Modulation of AP-1 by Natural Chemopreventive Compounds in Human Colon HT-29 Cancer Cell Line

Woo‐Sik Jeong, In‐Wha Kim, Rong Hu, +1

Pharmaceutical Research

OncologyChemoprevention StrategyMedicinePharmacologyNatural Chemopreventive Compounds +6

Epigenetic Changes in Gene Expression for Drug‐Metabolizing Enzymes and Transporters

In‐Wha Kim, Nayoung Han, Gilbert J. Burckart, +1

Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy