Pharmacogenetics

Pharmacogenetics is the subdiscipline of pharmacology that examines how genetic variation influences individual drug response and determines optimal medication selection and dosing.

24.8K

Publications

1.4M

Citations

113.7K

Authors

11.8K

Institutions

Publications per year

2017–2026

5.2K

Parents

Veterinary Pharmacology

Children

Adverse Drug ReactionsClinical Implementation Of PharmacogeneticsComparative PharmacogeneticsDose IndividualizationDrug Metabolism GeneticsDrug ResponseDrug Transporter GeneticsGene - Drug InteractionsGenetic VariationGenotype-phenotype Correlation

Publications

24.8K

Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region

Klaus‐Peter Lesch, Dietmar Bengel, Armin Heils et al. · Science · 1996 · 5.2K citations

Life Sciences, Genetics, Molecular Genetics +17

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

Dongliang Ge, Jacques Fellay, Alexander Thompson et al. · Nature · 2009 · 3.5K citations · Full text

Life Sciences, Genetics, Immunology +13

Metabolomics – the link between genotypes and phenotypes

Oliver Fiehn · Plant Molecular Biology · 2002 · 3.4K citations

Life Sciences, Biochemistry, Genetics +10

AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer

Emmanuel S. Antonarakis, Changxue Lu, Hao Wang et al. · New England Journal of Medicine · 2014 · 2.7K citations · Full text

Medicine, Oncology, Pharmacology +17

A "Silent" Polymorphism in the <i>MDR</i> 1 Gene Changes Substrate Specificity

Chava Kimchi‐Sarfaty, Jung Mi Oh, In‐Wha Kim et al. · Science · 2006 · 2.5K citations · Full text

Medicine, Genetics, Molecular Genetics +15

1–5 of 24.8K

Authors

113.7K

TE
Teri E. Klein
Stanford University, United States
103 publications · 25.2K citations
73
h-index
MS
Matthias Schwab
Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Germany
108 publications · 14.4K citations
62
h-index
MI
Magnus Ingelman‐Sundberg
Karolinska Institutet, Sweden
82 publications · 10.5K citations
59
h-index
AG
Andrea Gaedigk
Children's Mercy Hospital, United States
111 publications · 14.9K citations
56
h-index
ME
Michel Eichelbaum
Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Germany
75 publications · 13.7K citations
56
h-index

1–5 of 113.7K

Institutions

11.8K

1–8 of 11.8K

Venues

Clinical Pharmacology & Therapeutics
CPT · 718 publications · 87.2K citations
160
h-index
Pharmacogenetics
327 publications · 38.5K citations
112
h-index
PubMed
Repository · 912 publications · 45.1K citations
96
h-index
Pharmacogenetics and Genomics
650 publications · 37.8K citations
94
h-index
Molecular Psychiatry
135 publications · 17.9K citations
84
h-index

1–5

See also Pharmacogenetics
Genetic Variants	Cytochrome P450 2D6 Rare Genetic Variants Single-nucleotide Polymorphisms Copy Number Alterations Loss-of-function Variants Cytochrome P450 2C9
Drug Response	Pharmacokinetics Pharmacodynamics Drug Toxicity Adverse Drug Reactions Idiosyncratic Drug Reactions Interindividual Variability Drug Efficacy Assessment
Clinical Implementation	Pharmacogenetics Clinical Decision Support Clinical Decision Support Systems Electronic Health Records Preemptive Pharmacogenomic Testing Prescribing Workflow Design Collaborative Design Fast Healthcare Interoperability Resources Alert Fatigue
Testing Methods	Pharmacogenetics Next-generation Sequencing Cytochrome P450 Genotyping Polymerase Chain Reaction Multiplex Assay Validation
Population Differences	Population Structure Haplotype Diversity Analysis Ascertainment Bias Comparative Intravenous Pharmacokinetics Positive Selection