Antibody Optimization is a computational or experimental methodology aimed at enhancing the binding affinity, specificity, stability, and developability of chimeric antibodies through targeted modifications of their variable or constant regions.
270
Publications
15.2K
Citations
1.8K
Authors
469
Institutions
Publications per year
2017–2026
115
Parents
Publications
270
Engineered antibody Fc variants with enhanced effector function
Greg A. Lazar, Wei Dang, Sher Karki et al. · Proceedings of the National Academy of Sciences · 2006 · 794 citations · Full text
Optimizing antibody immobilization strategies for the construction of protein microarrays
Paul Peluso, David S. Wilson, Duc Do et al. · Analytical Biochemistry · 2003 · 518 citations
1–5 of 270
Authors
1.8K
- CM
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- PM
5
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- SJ
5
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- PD
4
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- TS
4
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1–5 of 1.8K
Institutions
469
Massachusetts Institute of Technology
Cambridge, United States
9 h-index
43 publications
4.3K citations
Scripps Research Institute
San Diego, United States
9 h-index
37 publications
2.1K citations
University of Oxford
Oxford, United Kingdom
8 h-index
18 publications
640 citations
Weizmann Institute of Science
Rehovot, Israel
7 h-index
46 publications
3.3K citations
The University of Tokyo
Tokyo, Japan
7 h-index
29 publications
1.3K citations
Amgen (United States)
Thousand Oaks, United States
6 h-index
30 publications
849 citations
University College London
London, United Kingdom
6 h-index
13 publications
451 citations
University of Michigan
Ann Arbor, United States
5 h-index
29 publications
2.8K citations
1–8 of 469
Venues
- mAbs
14 publications · 557 citations
14
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- PLoS ONE
11 publications · 526 citations
11
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- Proceedings of the National Academy of Sciences
PNAS · 10 publications · 2.3K citations
10
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- Journal of Immunological Methods
10 publications · 312 citations
10
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- Journal of Biological Chemistry
JBC · 10 publications · 883 citations
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