Derek M. Mason

Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning

Derek M. Mason, Simon Friedensohn, Cédric R. Weber et al. · Nature Biomedical Engineering · 2021 · 323 citations · Full text

Pharmacy, Bioinformatics, Immunology +17

Increased Incidence of Barotrauma in Patients with COVID-19 on Invasive Mechanical Ventilation

Georgeann McGuinness, Chenyang Zhan, Noah Rosenberg et al. · Radiology · 2020 · 300 citations · Full text

Medicine, Clinical Sciences, Infectious Diseases +12

High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis

Derek M. Mason, Cédric R. Weber, Cristina Parola et al. · Nucleic Acids Research · 2018 · 87 citations · Full text

Pharmacy, Biotechnology, Molecular Biology +17

A Single-Cell Atlas of Lymphocyte Adaptive Immune Repertoires and Transcriptomes Reveals Age-Related Differences in Convalescent COVID-19 Patients

Florian Bieberich, Rodrigo Vazquez-Lombardi, Alexander Yermanos et al. · Frontiers in Immunology · 2021 · 56 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

Deep learning enables therapeutic antibody optimization in mammalian cells by deciphering high-dimensional protein sequence space

Derek M. Mason, Simon Friedensohn, Cédric R. Weber et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2019 · 54 citations · Full text

Pharmacy, Biotechnology, Immunology +17