Alexander Yermanos

A novel anti-HER2 anthracycline-based antibody-drug conjugate induces adaptive anti-tumor immunity and potentiates PD-1 blockade in breast cancer

Lucia D’Amico, Ulrike Menzel, Michael Prummer et al. · Journal for ImmunoTherapy of Cancer · 2019 · 116 citations · Full text

Breast Oncology, Pd-1 Blockade, Adaptive Immune System +17

Deep mutational learning predicts ACE2 binding and antibody escape to combinatorial mutations in the SARS-CoV-2 receptor-binding domain

Joseph M. Taft, Cédric R. Weber, Beichen Gao et al. · Cell · 2022 · 111 citations · Full text

Viral Pathogenesis, Immunology, Molecular Biology +16

Tissue-resident CD8 ⁺ T cells drive compartmentalized and chronic autoimmune damage against CNS neurons

David Frieser, Aurora Pignata, Leila Khajavi et al. · Science Translational Medicine · 2022 · 86 citations · Full text

immuneSIM: tunable multi-feature simulation of B- and T-cell receptor repertoires for immunoinformatics benchmarking

Cédric R. Weber, Rahmad Akbar, Alexander Yermanos et al. · Bioinformatics · 2020 · 72 citations · Full text

Discovery and validation of human genomic safe harbor sites for gene and cell therapies

Erik Aznauryan, Alexander Yermanos, Elvira Kinzina et al. · Cell Reports Methods · 2022 · 69 citations · Full text

Engineering, In Vivo Gene Therapy, Genetics +20