Sher Karki - Concepedia

Author

Sher Karki

Xencor (United States)

Also Known As

S Karki, S. Karki, Sabanam Karki, Sher B. Karki, Sher Karki

142

Publications

6.5K

Citations

H-Index

Concepts

All Affiliations

Xencor (United States)University of Pennsylvania University of Santa Monica University of Rostock Christian-Albrechts-Universität zu Kiel

About

Sher Karki is an author at Xencor (United States) specializing in medicine, cell biology, and immunology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	13	13	3K
2	Natural Sciences	3	3	640
3	Engineering	1	1	107
4	Biomedical Engineering	1	1	50
5	Biomolecular Engineering	1	1	101

Sher Karki

Publications

5.9K

Citations

H-Index

Page 1

	Year	Citations
Engineered antibody Fc variants with enhanced effector function Greg A. Lazar, Wei Dang, Sher Karki, Proceedings of the National Academy of Sciences Engineered Fc RegionsNovel TherapyAntibody Fc VariantsMedicineImmunology	2006	783
Enfortumab Vedotin Antibody–Drug Conjugate Targeting Nectin-4 Is a Highly Potent Therapeutic Agent in Multiple Preclinical Cancer Models Pia M. Challita-Eid, Daulet Satpayev, Peng Yang, Cancer Research	2016	669
Enhanced antibody half-life improves in vivo activity Jonathan Zalevsky, Aaron K. Chamberlain, Holly M. Horton, Nature Biotechnology Antibody Half-life ImprovesImmunologyAntibody ScreeningAutoimmunityImmunochemistry	2010	625
Affinity Chromatography Demonstrates a Direct Binding between Cytoplasmic Dynein and the Dynactin Complex Sher Karki, Erika L.F. Holzbaur Journal of Biological Chemistry	1995	335
The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1). Clare M. Waterman, Sher Karki, Erika L.F. Holzbaur Proceedings of the National Academy of Sciences Molecular BiologyDynactin Complex BindsCytoskeletonCellular PhysiologyActin-related Protein Centractin	1995	307
Optimization of antibody binding to FcγRIIa enhances macrophage phagocytosis of tumor cells John O. Richards, Sher Karki, Greg A. Lazar, Molecular Cancer Therapeutics	2008	296
Dynein binds to β-catenin and may tether microtubules at adherens junctions Lee A. Ligon, Sher Karki, Mariko Tokito, Nature Cell Biology Cell AdhesionMolecular BiologyAdherens JunctionsCell-matrix InteractionCell Motility	2001	293
Potent <i>In vitro</i> and <i>In vivo</i> Activity of an Fc-Engineered Anti-CD19 Monoclonal Antibody against Lymphoma and Leukemia Holly M. Horton, Matthew J. Bernett, Erik Pong, Cancer Research	2008	267
The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport Clare M. Waterman, Sher Karki, Joel S. Tabb, Proceedings of the National Academy of Sciences	1997	256
Engineered Fc variant antibodies with enhanced ability to recruit complement and mediate effector functions Gregory L. Moore, Hsing Chen, Sher Karki, mAbs	2010	252

Page 1