Xencor (United States)

Engineered antibody Fc variants with enhanced effector function

Greg A. Lazar, Wei Dang, Sher Karki et al. · Proceedings of the National Academy of Sciences · 2006 · 783 citations · Full text

Engineered Fc Regions, Novel Therapy, Antibody Fc Variants +13

Enhanced antibody half-life improves in vivo activity

Jonathan Zalevsky, Aaron K. Chamberlain, Holly M. Horton et al. · Nature Biotechnology · 2010 · 625 citations · Full text

Antibody Half-life Improves, Immunology, Antibody Screening +5

Transcriptional Regulation of Biomass-degrading Enzymes in the Filamentous Fungus Trichoderma reesei

Pamela K. Foreman, Doug Brown, Lydia Dankmeyer et al. · Journal of Biological Chemistry · 2003 · 484 citations · Full text

JNK and Tumor Necrosis Factor-α Mediate Free Fatty Acid-induced Insulin Resistance in 3T3-L1 Adipocytes

Matthew Nguyen, Hiroaki Satoh, Svetlana Favelyukis et al. · Journal of Biological Chemistry · 2005 · 402 citations · Full text

Immunology, Activated Jnk, Insulin Signaling +18

Characterizing biological products and assessing comparability following manufacturing changes

Arthur J. Chirino, Anthony R. Mire‐Sluis · Nature Biotechnology · 2004 · 361 citations

Biomanufacturing, Engineering, Agricultural Economics +8