Greg A. Lazar

Engineered antibody Fc variants with enhanced effector function

Greg A. Lazar, Wei Dang, Sher Karki et al. · Proceedings of the National Academy of Sciences · 2006 · 794 citations · Full text

Pharmacy, Computational Design, Immunology +17

Enhanced antibody half-life improves in vivo activity

Jonathan Zalevsky, Aaron K. Chamberlain, Holly M. Horton et al. · Nature Biotechnology · 2010 · 644 citations · Full text

Pharmacy, Immunology, Pharmacokinetics +12

Optimization of antibody binding to FcγRIIa enhances macrophage phagocytosis of tumor cells

John O. Richards, Sher Karki, Greg A. Lazar et al. · Molecular Cancer Therapeutics · 2008 · 304 citations

Life Sciences, Cell Biology, Immunology +17

Engineered Fc variant antibodies with enhanced ability to recruit complement and mediate effector functions

Gregory L. Moore, Hsing Chen, Sher Karki et al. · mAbs · 2010 · 257 citations · Full text

Pharmacy, Immunology, Oncology +17

De novo design of the hydrophobic core of ubiquitin

Greg A. Lazar, John R. Desjarlais, Tracy M. Handel · Protein Science · 1997 · 185 citations

Life Sciences, Biochemistry, Molecular Biology +17