Greg A. Lazar

Engineered antibody Fc variants with enhanced effector function

Greg A. Lazar, Wei Dang, Sher Karki et al. · Proceedings of the National Academy of Sciences · 2006 · 783 citations · Full text

Engineered Fc Regions, Novel Therapy, Antibody Fc Variants +13

Enhanced antibody half-life improves in vivo activity

Jonathan Zalevsky, Aaron K. Chamberlain, Holly M. Horton et al. · Nature Biotechnology · 2010 · 625 citations · Full text

Antibody Half-life Improves, Immunology, Antibody Screening +5

Optimization of antibody binding to FcγRIIa enhances macrophage phagocytosis of tumor cells

John O. Richards, Sher Karki, Greg A. Lazar et al. · Molecular Cancer Therapeutics · 2008 · 296 citations

Engineered Fc variant antibodies with enhanced ability to recruit complement and mediate effector functions

Gregory L. Moore, Hsing Chen, Sher Karki et al. · mAbs · 2010 · 252 citations · Full text

De novo design of the hydrophobic core of ubiquitin

Greg A. Lazar, John R. Desjarlais, Tracy M. Handel · Protein Science · 1997 · 183 citations