Hsing Chen

Optimization of antibody binding to FcγRIIa enhances macrophage phagocytosis of tumor cells

John O. Richards, Sher Karki, Greg A. Lazar et al. · Molecular Cancer Therapeutics · 2008 · 296 citations

Engineered Fc variant antibodies with enhanced ability to recruit complement and mediate effector functions

Gregory L. Moore, Hsing Chen, Sher Karki et al. · mAbs · 2010 · 252 citations · Full text

Reduction of total IgE by targeted coengagement of IgE B-cell receptor and FcγRIIb with Fc-engineered antibody

Seung Y. Chu, Holly M. Horton, Erik Pong et al. · Journal of Allergy and Clinical Immunology · 2012 · 92 citations

Fc-engineered Antibody, Targeted Coengagement, Immunology +12

Fc-engineered anti-CD40 antibody enhances multiple effector functions and exhibits potent in vitro and in vivo antitumor activity against hematologic malignancies

Holly M. Horton, Matthew J. Bernett, Matthias Peipp et al. · Blood · 2010 · 73 citations · Full text

Suppression of Rheumatoid Arthritis B Cells by XmAb5871, an Anti‐CD19 Antibody That Coengages B Cell Antigen Receptor Complex and Fcγ Receptor IIb Inhibitory Receptor

Seung Y. Chu, Karen Yeter, Roshan Kotha et al. · Arthritis & Rheumatology · 2013 · 63 citations