Concepedia

K. Dane Wittrup

KD

186

Publications

21.2K

Citations

76

H-Index

1988

Active since

Affiliations

Massachusetts Institute of Technology(Current)

University of Illinois Urbana-Champaign

Ragon Institute of MGH, MIT and Harvard

Howard Hughes Medical Institute

Harvard University

K. Dane Wittrup is an author at Massachusetts Institute of Technology specializing in medicine, immunology, and cell biology.

Top concepts

MedicineImmunologyCell BiologyImmunotherapyMolecular BiologyAntibody EngineeringNatural SciencesEngineeringBiomolecular EngineeringProtein Engineering

Publications per year

1988–2024

186

Publications

186

Yeast surface display for screening combinatorial polypeptide libraries

Eric T. Boder, K. Dane Wittrup · Nature Biotechnology · 1997 · 1.8K citations

Natural Sciences, Peptide Library, Molecular Biology +5

Isolating and engineering human antibodies using yeast surface display

Ginger Chao, Wai Leung Lau, Benjamin J. Hackel et al. · Nature Protocols · 2006 · 937 citations

Engineering, Biotechnology, Synthetic Biology +5

Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity

Eric T. Boder, Katarina S. Midelfort, K. Dane Wittrup · Proceedings of the National Academy of Sciences · 2000 · 686 citations · Full text

Biophysical properties of the clinical-stage antibody landscape

Tushar Jain, Tingwan Sun, Stéphanie Durand et al. · Proceedings of the National Academy of Sciences · 2017 · 600 citations · Full text

Immunocytochemical Technique, Engineering, Immunology +18

A modeling analysis of the effects of molecular size and binding affinity on tumor targeting

Michael M. Schmidt, K. Dane Wittrup · Molecular Cancer Therapeutics · 2009 · 559 citations · Full text

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