Joseph F. Kelleher - Concepedia

Author

Joseph F. Kelleher

Genomics Institute of the Novartis Research Foundation

Also Known As

J F Kelleher, J. F. Kelleher, J. Kelleher, J.F. Kelleher, JOSEPH F. KELLEHER, Joseph F Kelleher, Joseph F. Kelleher, Joseph Kelleher, Joseph F. Kelleher, Justin Kelleher

Publications

3.6K

Citations

H-Index

Concepts

All Affiliations

Genomics Institute of the Novartis Research Foundation Novartis (United States)Novartis Institutes for BioMedical Research Novartis (Switzerland)Johns Hopkins University

About

Joseph F. Kelleher is an author at Genomics Institute of the Novartis Research Foundation specializing in medicine, cell biology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	16	16	2.3K
2	Cell Biology	9	9	1.8K
3	Natural Sciences	5	5	593
4	Biochemistry	4	4	460
5	Health Sciences	3	3	278

Joseph F. Kelleher

Publications

Citations

H-Index

Page 1

	Year	Citations
Interfering with Resistance to Smoothened Antagonists by Inhibition of the PI3K Pathway in Medulloblastoma Silvia Buonamici, Juliet Williams, Michael Morrissey, Science Translational Medicine	2010	553
Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist Shifeng Pan, Xu Wu, Jiqing Jiang, ACS Medicinal Chemistry Letters Selective Smoothened AntagonistChemoprevention StrategyNovel TherapyFunctional SelectivityMedicine	2010	325
Essential role of stromally induced hedgehog signaling in B-cell malignancies Christine Dierks, Jovana Grbic, Katja Zirlik, Nature Medicine Tumor BiologySignaling PathwayEssential RoleCell RegulationMalignant Blood Disorder	2007	321
Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway Zainab Jagani, E. Lorena Mora‐Blanco, Courtney G. Sansam, Nature Medicine Signaling PathwayMedicinePathologyTumor SuppressorCancer Genetics	2010	252
Sequences, structural models, and cellular localization of the actin-related proteins Arp2 and Arp3 from Acanthamoeba. Joseph F. Kelleher, Simon J. Atkinson, Thomas D. Pollard The Journal of Cell Biology Cellular LocalizationMolecular BiologyCytoskeletonActin PolymerizationStructural Models	1995	191
Abscisic Acid-Induced Phosphoinositide Turnover in Guard Cell Protoplasts of Vicia faba Youngsook Lee, Yoori Choi, Suk‐Hwan Suh, PLANT PHYSIOLOGY Abscisic AcidCellular PhysiologyBiosynthesisVicia FabaCell Signaling	1996	187
RAS/MAPK Activation Drives Resistance to Smo Inhibition, Metastasis, and Tumor Evolution in Shh Pathway–Dependent Tumors Xuesong Zhao, Tatyana Ponomaryov, Kimberly J. Ornell, Cancer Research Smo InhibitionCancer BiologyTumor BiologyDrug ResistanceSignaling Pathway	2015	167
Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities Mariella G. Filbin, Sukriti K. Dabral, Maria F. Pazyra‐Murphy, Nature Medicine Neuro-oncologyPten-deficient GlioblastomaSignal TransductionSignaling PathwayGlioma	2013	150
Topical Treatment of Basal Cell Carcinomas in Nevoid Basal Cell Carcinoma Syndrome with a Smoothened Inhibitor Hans Skvara, Frank Kalthoff, Josef G. Meingassner, Journal of Investigative Dermatology Neuro-oncologySmoothened InhibitorDermatologyTopical TreatmentMedicine	2011	148
1-Amino-4-benzylphthalazines as Orally Bioavailable Smoothened Antagonists with Antitumor Activity Karen Miller‐Moslin, Stefan Peukert, Rishi K. Jain, Journal of Medicinal Chemistry Pharmaceutical ScienceAntitumor ActivityPharmacotherapyPharmaceutical ChemistryTumor Biology	2009	106

Page 1