Bertil Samuelsson

Discovery and Development of Simeprevir (TMC435), a HCV NS3/4A Protease Inhibitor

Åsa Rosenquist, Bertil Samuelsson, Per-Ola Johansson et al. · Journal of Medicinal Chemistry · 2014 · 215 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

In Vitro Activity and Preclinical Profile of TMC435350, a Potent Hepatitis C Virus Protease Inhibitor

Tse‐I Lin, Oliver Lenz, Gregory Fanning et al. · Antimicrobial Agents and Chemotherapy · 2009 · 190 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Relationships between Structure and Interaction Kinetics for HIV-1 Protease Inhibitors

Per-Olof Markgren, Wesley Schaal, Markku Hämäläinen et al. · Journal of Medicinal Chemistry · 2002 · 150 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +16

Characterization of the human 5-lipoxygenase gene promoter.

Shigeru Hoshiko, Olof Rådmark, Bertil Samuelsson · Proceedings of the National Academy of Sciences · 1990 · 139 citations

Life Sciences, Biochemistry, Molecular Biology +17

Structure–activity relationship study on a novel series of cyclopentane-containing macrocyclic inhibitors of the hepatitis C virus NS3/4A protease leading to the discovery of TMC435350

Pierre Raboisson, Herman de Kock, Åsa Rosenquist et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 136 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16