Tse‐I Lin

<i>In Vitro</i> Resistance Profile of the Hepatitis C Virus NS3/4A Protease Inhibitor TMC435

Oliver Lenz, Thierry Verbinnen, Tse‐I Lin et al. · Antimicrobial Agents and Chemotherapy · 2010 · 211 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

In Vitro Activity and Preclinical Profile of TMC435350, a Potent Hepatitis C Virus Protease Inhibitor

Tse‐I Lin, Oliver Lenz, Gregory Fanning et al. · Antimicrobial Agents and Chemotherapy · 2009 · 190 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure–activity relationship study on a novel series of cyclopentane-containing macrocyclic inhibitors of the hepatitis C virus NS3/4A protease leading to the discovery of TMC435350

Pierre Raboisson, Herman de Kock, Åsa Rosenquist et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 136 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Induced‐Fit Binding of the Macrocyclic Noncovalent Inhibitor TMC435 to its HCV NS3/NS4A Protease Target

Maxwell D. Cummings, Jimmy Lindberg, Tse‐I Lin et al. · Angewandte Chemie International Edition · 2010 · 95 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Regulation of gene transcription by thyroid hormone receptor β agonists in clinical development for the treatment of non-alcoholic steatohepatitis (NASH)

Xuan G. Luong, Sarah Stevens, Andreas Jekle et al. · PLoS ONE · 2020 · 68 citations · Full text

Medicine, Endocrinology, Pharmacology +14