Åsa Rosenquist

Discovery and Development of Simeprevir (TMC435), a HCV NS3/4A Protease Inhibitor

Åsa Rosenquist, Bertil Samuelsson, Per-Ola Johansson et al. · Journal of Medicinal Chemistry · 2014 · 215 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

In Vitro Activity and Preclinical Profile of TMC435350, a Potent Hepatitis C Virus Protease Inhibitor

Tse‐I Lin, Oliver Lenz, Gregory Fanning et al. · Antimicrobial Agents and Chemotherapy · 2009 · 190 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure–activity relationship study on a novel series of cyclopentane-containing macrocyclic inhibitors of the hepatitis C virus NS3/4A protease leading to the discovery of TMC435350

Pierre Raboisson, Herman de Kock, Åsa Rosenquist et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 136 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Induced‐Fit Binding of the Macrocyclic Noncovalent Inhibitor TMC435 to its HCV NS3/NS4A Protease Target

Maxwell D. Cummings, Jimmy Lindberg, Tse‐I Lin et al. · Angewandte Chemie International Edition · 2010 · 95 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Identification of a Potent Heterocyclic Ligand To Somatostatin Receptor Subtype 5 by the Synthesis and Screening of β-Turn Mimetic Libraries

Andrew J. Souers, Alex A. Virgilio, Åsa Rosenquist et al. · Journal of the American Chemical Society · 1999 · 81 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17