Per-Ola Johansson

Discovery and Development of Simeprevir (TMC435), a HCV NS3/4A Protease Inhibitor

Åsa Rosenquist, Bertil Samuelsson, Per-Ola Johansson et al. · Journal of Medicinal Chemistry · 2014 · 215 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Design and Synthesis of Potent Inhibitors of the Malaria Aspartyl Proteases Plasmepsin I and II. Use of Solid-Phase Synthesis to Explore Novel Statine Motifs

Per-Ola Johansson, Yantao Chen, Anna Karin Belfrage et al. · Journal of Medicinal Chemistry · 2004 · 50 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Design and Synthesis of Potent Inhibitors of Plasmepsin I and II:  X-ray Crystal Structure of Inhibitor in Complex with Plasmepsin II

Per-Ola Johansson, Jimmy Lindberg, Michael J. Blackman et al. · Journal of Medicinal Chemistry · 2005 · 39 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Novel potent macrocyclic inhibitors of the hepatitis C virus NS3 protease: Use of cyclopentane and cyclopentene P2-motifs

Marcus Bäck, Per-Ola Johansson, Fredrik Wångsell et al. · Bioorganic & Medicinal Chemistry · 2007 · 33 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Highly potent macrocyclic BACE-1 inhibitors incorporating a hydroxyethylamine core: Design, synthesis and X-ray crystal structures of enzyme inhibitor complexes

Veronica Sandgren, Tatiana Agback, Per-Ola Johansson et al. · Bioorganic & Medicinal Chemistry · 2012 · 27 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17