Anna Karin Belfrage

Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors

Jürgen Brem, Tharindi Panduwawala, Jon Hansen et al. · Nature Chemistry · 2021 · 77 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Antimicrobial Drug Discovery +11

Design and Synthesis of Potent Inhibitors of the Malaria Aspartyl Proteases Plasmepsin I and II. Use of Solid-Phase Synthesis to Explore Novel Statine Motifs

Per-Ola Johansson, Yantao Chen, Anna Karin Belfrage et al. · Journal of Medicinal Chemistry · 2004 · 50 citations · Full text

Synthesis and SAR of potent inhibitors of the Hepatitis C virus NS3/4A protease: Exploration of P2 quinazoline substituents

Magnus Nilsson, Anna Karin Belfrage, Stefan B. Lindström et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 24 citations

Biochemistry, Medicine, Antiviral Drug Development +7

Achiral Pyrazinone-Based Inhibitors of the Hepatitis C Virus NS3 Protease and Drug-Resistant Variants with Elongated Substituents Directed Toward the S2 Pocket

Johan Gising, Anna Karin Belfrage, Hiba Alogheli et al. · Journal of Medicinal Chemistry · 2013 · 23 citations · Full text

Molecular Biology, Peptide Science, Antiviral Drug +25

Discovery of 4′-azido-2′-deoxy-2′-C-methyl cytidine and prodrugs thereof: A potent inhibitor of Hepatitis C virus replication

Magnus Nilsson, Genadiy Kalayanov, Anna Winqvist et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 19 citations

Potent Inhibitor, Viral Hepatitis, Drug Discovery +10