Concepedia

Jürgen Brem

JB

Statistics

Publications

73

Citations

3.3K

H-Index

32

Active since

2009

Affiliations

University of Oxford(Current)

University of Bristol

Babeș-Bolyai University

Mansfield University

Jürgen Brem is an author at University of Oxford specializing in beta-lactam resistance, beta-lactamase inhibitors, and β-lactam antibiotics.

Publications per year

2009–2024

73

Publications

73

Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates

Jürgen Brem, Ricky Cain, Samuel T. Cahill et al. · Nature Communications · 2016 · 246 citations · Full text

Pharmacy, Medicinal Chemistry, Drug Discovery +15

Bicyclic Boronate VNRX-5133 Inhibits Metallo- and Serine-β-Lactamases

Alen Krajnc, Jürgen Brem, Philip Hinchliffe et al. · Journal of Medicinal Chemistry · 2019 · 202 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers

Jürgen Brem, Sander S. van Berkel, David Zollman et al. · Antimicrobial Agents and Chemotherapy · 2015 · 161 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16

Insights into the Mechanistic Basis of Plasmid-Mediated Colistin Resistance from Crystal Structures of the Catalytic Domain of MCR-1

Philip Hinchliffe, Qiu E. Yang, Edward Portal et al. · Scientific Reports · 2017 · 139 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

Assay Platform for Clinically Relevant Metallo-β-lactamases

Sander S. van Berkel, Jürgen Brem, Anna M. Rydzik et al. · Journal of Medicinal Chemistry · 2013 · 129 citations · Full text

Medicine, Pharmacology, Antimicrobial Pharmacology +15

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