Fredrik Wångsell

Use of a HEHEHE Purification Tag Instead of a Hexahistidine Tag Improves Biodistribution of Affibody Molecules Site-Specifically Labeled with ^99mTc, ¹¹¹In, and ¹²⁵I

Camilla Hofström, Anna Orlova, Mohamed Altai et al. · Journal of Medicinal Chemistry · 2011 · 61 citations

Medicine, Molecular Biology, Nuclear Medicine +17

A3907, a systemic ASBT inhibitor, improves cholestasis in mice by multiorgan activity and shows translational relevance to humans

Francisco J. Caballero‐Camino, Pedro M. Rodrigues, Fredrik Wångsell et al. · Hepatology · 2023 · 37 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Novel potent macrocyclic inhibitors of the hepatitis C virus NS3 protease: Use of cyclopentane and cyclopentene P2-motifs

Marcus Bäck, Per-Ola Johansson, Fredrik Wångsell et al. · Bioorganic & Medicinal Chemistry · 2007 · 33 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Synthesis of potent BACE-1 inhibitors incorporating a hydroxyethylene isostere as central core

Fredrik Wångsell, Karin Gustafsson, Ingemar Kvarnström et al. · European Journal of Medicinal Chemistry · 2009 · 22 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Investigation of α-phenylnorstatine and α-benzylnorstatine as transition state isostere motifs in the search for new BACE-1 inhibitors

Fredrik Wångsell, Patrik Nordeman, Jonas Sävmarker et al. · Bioorganic & Medicinal Chemistry · 2010 · 19 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12